Rosalind Franklin: Photo 51, X-Ray Crystallography & DNA Structure
Encyclopedia/1. The Cosmos & The Natural World/6. Medicine & Human Biology/07. Medical & Health Biographies • Curated by Admin Timeline.sg
Timeline of Rosalind Franklin (1920-1958), the physical chemist and X-ray crystallographer whose work was crucial to understanding DNA structure, and her lasting legacy in science.
Chronological Storyline (39 Milestones)
Jul 25, 1920 CE
Birth in London
Rosalind Elsie Franklin is born to a wealthy Jewish family in Notting Hill, London. She will later become a pioneer in X-ray crystallography. #science #womeninscience
Birth in London By MRC Laboratory of Molecular Biology - This file was derived from: Rosalind Franklin.jpg:, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=77075413
Sep 1, 1926 CE
Attends Norland Place School
Franklin begins her education at Norland Place School in London, showing early aptitude for science and mathematics. #education #science
Attends Norland Place School By Norland Place - Norland Place School, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=93237055
Sep 1, 1931 CE
Enters St Paul's Girls' School
Franklin earns a scholarship to St Paul's Girls' School, where she excels in science and languages, winning a school science prize in 1936. #education #womeninscience
Enters St Paul's Girls' School By Chmee2 - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=25505761
Oct 1, 1938 CE
Begins Studies at Newnham College, Cambridge
Franklin enrolls at Newnham College, Cambridge, to study natural sciences, specializing in physical chemistry. #education #science
Begins Studies at Newnham College, Cambridge By Cmglee - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=32161742
Jun 1, 1941 CE
Graduates with First-Class BA
Franklin graduates with a first-class BA in physical chemistry from Cambridge, but she is not awarded a full degree because women were not then eligible. #science #history
Aug 1, 1942 CE
Begins Research at BCURA
Franklin joins the British Coal Utilisation Research Association (BCURA) during World War II, studying the porosity of coal to improve gas masks. #science #wwii
Aug 1, 1945 CE
Awarded PhD from Cambridge
Franklin is awarded a PhD in physical chemistry for her thesis on the micromeritics of coal, based on her BCURA research. #science #education
Feb 1, 1946 CE
Publishes First Major Paper on Coal
Franklin publishes a paper on the structure of coal in Transactions of the Faraday Society, establishing her reputation in physical chemistry. #science #chemistry
Jan 1, 1947 CE
Moves to Paris for X-Ray Crystallography
Franklin takes a position at the Laboratoire Central des Services Chimiques de l'État in Paris, where she learns X-ray crystallography techniques under Jacques Mering. #science #crystallography
Jun 1, 1948 CE
Publishes Work on Carbon Structure
Franklin publishes a seminal paper on structural changes in carbons upon heat treatment, providing insights into graphitization. #science #chemistry
Feb 1, 1950 CE
Influential Paper on Coal Microporosity
Franklin's work on the microporosity of coals becomes a key reference in coal science, demonstrating her skill in physical chemistry. #science #chemistry
Jan 1, 1951 CE
Appointed at King's College London
Franklin is appointed as a research associate at King's College London's MRC Biophysics Unit, tasked with applying X-ray diffraction to DNA. #science #DNA
Appointed at King's College London By Hogweard - Arms of King's College London.svg King's College, London arms.svg, Public domain, https://commons.wikimedia.org/w/index.php?curid=125206690
Nov 21, 1951 CE
Seminar on DNA X-Ray Diffraction
Franklin presents a seminar on her initial DNA X-ray diffraction data, but James Watson misremembers and underestimates her work. #science #DNA
May 6, 1952 CE
Captures Photo 51
Franklin and graduate student Raymond Gosling capture the iconic X-ray diffraction image Photo 51, revealing the B form of DNA with a helical structure. #science #DNA #photo51
Captures Photo 51 By Raymond Gosling - King's College London Archives: KDBP1/1/867. Taken from "The double helix: “Photo 51” revisited" by Thoru Pederson (https://doi.org/10.1096/fj.202000119), PD, https://en.wikipedia.org/w/index.php?curid=38068629
Nov 1, 1952 CE
Completes Analysis of DNA A-Form
Franklin carefully analyzes and indexes the diffraction pattern of the A form of DNA, deducing its space group and symmetry. #science #DNA
Jan 28, 1953 CE
Records B-Form Helical Parameters
Franklin notes in her lab book that the B form of DNA is a helix with a specific diameter and pitch, contradicting earlier models. #science #DNA
Feb 28, 1953 CE
Wilkins Shows Photo 51 to Watson
Without Franklin's knowledge, Maurice Wilkins shows Photo 51 to James Watson, who immediately recognizes the helical structure, catalyzing the double helix model. #science #DNA
Apr 25, 1953 CE
Watson and Crick Publish DNA Double Helix Model
Francis Crick and James Watson publish the double helix model of DNA in Nature, citing Franklin's data and acknowledging her contribution. #science #DNA
Watson and Crick Publish DNA Double Helix Model By 84user adapting file originally uploaded by Richard Wheeler (Zephyris) at en.wikipedia - Derived from File:DNA orbit animated.gif originally from here., CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=6285050
Jul 1, 1953 CE
Moves to Birkbeck College
Franklin leaves King's College London and joins Birkbeck College, where she shifts focus to the Tobacco Mosaic Virus (TMV). #science #career
Moves to Birkbeck College By Robin S. Taylor - Own work, with helmet by Sodacan, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=80107375
Aug 1, 1953 CE
Publishes DNA Papers in Nature
Franklin and Gosling publish two companion papers in Nature describing X-ray diffraction of both A and B forms of DNA, providing key evidence for the double helix. #science #DNA
Oct 1, 1953 CE
Begins TMV Research at Birkbeck
Franklin starts her research on Tobacco Mosaic Virus, applying her crystallography skills to understand virus structure. #science #virology
Begins TMV Research at Birkbeck By Unknown author - [1], Public domain, https://commons.wikimedia.org/w/index.php?curid=3430584
Mar 1, 1954 CE
Obtains First TMV Diffraction Pattern
Franklin successfully obtains the first X-ray diffraction pattern of Tobacco Mosaic Virus, confirming its helical structure. #science #virology
Jun 1, 1955 CE
Publishes TMV Structure Paper
Franklin publishes a major paper on the structure of Tobacco Mosaic Virus, showing the helical arrangement of protein subunits and RNA. #science #virology
Sep 1, 1956 CE
Diagnosed with Ovarian Cancer
Franklin is diagnosed with ovarian cancer, possibly linked to radiation exposure. She undergoes surgery and treatment. #science #health
Mar 20, 1957 CE
Returns to Research After Surgery
Franklin returns to her research at Birkbeck after surgery, continuing her work on TMV with a small team. #science #perseverance
Feb 1, 1958 CE
Publishes Final TMV Paper with Klug
Franklin and Aaron Klug publish a paper on the structure of TMV, marking her last major contribution before her death. #science #virology
Apr 16, 1958 CE
Death in London
Rosalind Franklin dies at age 37 in Chelsea, London, due to complications from ovarian cancer. #science #history
Dec 10, 1962 CE
Nobel Prize Awarded to Watson, Crick, Wilkins
The Nobel Prize in Physiology or Medicine is awarded to James Watson, Francis Crick, and Maurice Wilkins for the structure of DNA. Franklin, who died in 1958, is not eligible. #science #DNA #nobel
Feb 25, 1968 CE
Watson Publishes 'The Double Helix'
James Watson's memoir 'The Double Helix' portrays Franklin in a negative light, sparking controversy and efforts to correct the record. #science #history #books
Aug 15, 1975 CE
Biography 'Rosalind Franklin and DNA' Published
Anne Sayre's biography 'Rosalind Franklin and DNA' provides a detailed and corrective account of Franklin's contributions. #science #books #womeninscience
Nov 15, 1982 CE
Blue Plaque Commemorates Franklin
A blue plaque is unveiled at her childhood home in London, recognizing her important scientific legacy. #history #womeninscience
Oct 1, 1992 CE
King's College Establishes Franklin Fellowship
King's College London establishes a Rosalind Franklin Research Fellowship to support women in science. #education #womeninscience
Apr 25, 2003 CE
Nature Special Issue on DNA 50th Anniversary
Nature publishes a special issue honoring the 50th anniversary of the DNA double helix, highlighting Franklin's pivotal role. #science #DNA #history
Nov 1, 2004 CE
Royal Society Creates Rosalind Franklin Award
The Royal Society establishes the Rosalind Franklin Award, recognizing contributions of women in science and supporting their careers. #science #womeninscience #award
Nov 1, 2008 CE
ExoMars Rover Named Rosalind Franklin
The European Space Agency names its ExoMars rover 'Rosalind Franklin,' honoring her contributions to science. #space #science )
ExoMars Rover Named Rosalind Franklin By Photograph by Mike Peel (www.mikepeel.net). - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=177261072
Mar 1, 2012 CE
Royal Mail Stamp Featuring Franklin
The UK Royal Mail issues a stamp featuring Rosalind Franklin as part of its 'Women of Achievement' series. #history #science
Jul 25, 2015 CE
Statue of Franklin Unveiled at King's College
A statue of Rosalind Franklin is unveiled at King's College London, ensuring her legacy remains visible. #history #science #womeninscience
Jul 25, 2020 CE
Google Doodle for 100th Birthday
Google commemorates Rosalind Franklin's 100th birthday with a Doodle highlighting her DNA discovery. #science #DNA #womeninscience
Sep 1, 2022 CE
ExoMars Rover Begins Journey (Delayed)
The ExoMars rover 'Rosalind Franklin' begins its delayed mission to search for signs of past life on Mars, carrying her name into space. #space #science )