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Neuroscience & Brain Mapping

Encyclopedia/1. The Cosmos & The Natural World/2. Physics & Chemistry/10. Foundational & General Physics  •  Curated by Admin Timeline.sg

This timeline traces the foundational milestones in neuroscience and brain mapping from ancient times to the early 20th century, highlighting key discoveries about brain structure, function, and the nervous system that laid the groundwork for modern neuroscience.

Chronological Storyline (51 Milestones)

1700 BCE

Edwin Smith Surgical Papyrus Describes Brain

The Edwin Smith Papyrus, an ancient Egyptian medical text, contains the earliest known reference to the brain, describing its surface, meninges, and cerebrospinal fluid. It also notes that brain injuries can affect motor function on the opposite side of the body. #neuroscience #history #medicine

Edwin Smith Surgical Papyrus Describes Brain
Edwin Smith Surgical Papyrus Describes Brain
By Jeff Dahl - Edited version of Image:EdSmPaPlateVIandVIIPrintsx.jpg, Public domain, https://commons.wikimedia.org/w/index.php?curid=2854143
500 BCE

Alcmaeon of Croton Identifies the Brain as Seat of Intelligence

Greek philosopher and physician Alcmaeon of Croton proposed that the brain, not the heart, is the center of sensation and thought. He conducted dissections and discovered the optic nerves, linking the eyes to the brain. #neuroscience #history #philosophy

Alcmaeon of Croton Identifies the Brain as Seat of Intelligence
Alcmaeon of Croton Identifies the Brain as Seat of Intelligence
By Unknown author - http://archiviostoricoarborensemarrubiu.blogspot.ru/2015/04/scheda-04-n-9-storia-della-medicina.html http://www.ilportaledelsud.org/medagliere_di_rauso_1.htm http://www.ilportaledelsud.org/medagliere_di_rauso_1.htm, Public domain, https://commons.wikimedia.org/w/index.php?curid=16747402
400 BCE

Hippocrates Describes Epilepsy as a Brain Disorder

Hippocrates, the 'Father of Medicine,' wrote 'On the Sacred Disease,' arguing that epilepsy is not a divine punishment but a brain disorder. He emphasized the brain's role in controlling the body and intellect. #neuroscience #history #medicine

Hippocrates Describes Epilepsy as a Brain Disorder
Hippocrates Describes Epilepsy as a Brain Disorder
By Unidentified engraver - 1881 Young Persons' Cyclopedia of Persons and Places Upload by RedWolf 05:45, Jan 10, 2005 (UTC), Public domain, https://commons.wikimedia.org/w/index.php?curid=164808
335 BCE

Aristotle Advocates Cardiocentric View

Aristotle argued that the heart is the seat of intelligence and sensation, relegating the brain to a cooling function for the blood. This cardiocentric view persisted for centuries, despite earlier evidence for the brain. #neuroscience #history #philosophy

Aristotle Advocates Cardiocentric View
Aristotle Advocates Cardiocentric View
By After Lysippos - Jastrow (2006), Public domain, https://commons.wikimedia.org/w/index.php?curid=1359807
280 BCE

Herophilus Dissects Human Brain and Identifies Ventricles

Herophilus of Chalcedon, a Greek anatomist, performed systematic dissections of human brains and distinguished the cerebrum from the cerebellum. He identified the ventricles and described the calamus scriptorius. #neuroscience #history #anatomy

Herophilus Dissects Human Brain and Identifies Ventricles
Herophilus Dissects Human Brain and Identifies Ventricles
By Ecelan - Own work, CC BY-SA 3.0 es, https://commons.wikimedia.org/w/index.php?curid=16641053
250 BCE

Erasistratus Links Brain to Nerves and Intelligence

Erasistratus of Ceos, a Greek anatomist, distinguished sensory and motor nerves and proposed that the brain's convolutions are related to intelligence. He also described the cerebral ventricles and their role in animal spirits. #neuroscience #history #anatomy

Erasistratus Links Brain to Nerves and Intelligence
Erasistratus Links Brain to Nerves and Intelligence
By Didier Descouens - Own work, Public domain, https://commons.wikimedia.org/w/index.php?curid=90209212
177 CE

Galen Describes Cranial Nerves and Brain Function

Roman physician Galen conducted extensive animal dissections and described seven of the twelve cranial nerves. He proposed that the brain controls movement and sensation via a system of ventricles and animal spirits. #neuroscience #history #medicine

Galen Describes Cranial Nerves and Brain Function
Galen Describes Cranial Nerves and Brain Function
By Georg Paul Busch (engraver) - The Lancet, Public domain, https://commons.wikimedia.org/w/index.php?curid=40855568
1000 CE

Al-Zahrawi Develops Neurosurgical Instruments

Andalusian surgeon Al-Zahrawi (Abulcasis) wrote 'Al-Tasrif,' a medical encyclopedia describing surgical instruments and techniques for treating head injuries, skull fractures, and spinal disorders. He is considered a pioneer of neurosurgery. #neuroscience #history #surgery

1316 CE

Mondino de Luzzi Publishes First Anatomy Textbook

Mondino de Luzzi, an Italian anatomist, wrote 'Anathomia,' the first European anatomy text based on human dissection. He described the brain's ventricles and meninges, reviving interest in neuroanatomy. #neuroscience #history #anatomy

Mondino de Luzzi Publishes First Anatomy Textbook
Mondino de Luzzi Publishes First Anatomy Textbook
By Unknown author - Transferred from de.wikipedia to Commons. Dieses aus: Geschichte der Medizin, Website bei der Universität Erlangen Laut Franco Bacchellis Artikel Liuzzi, Mondino de' in Dizionario Biografico degli Italiani, Band 65 (2005), handelt es sich um die Titelseite der Leipziger Ausgabe der Anothomia von 1493 - wiedergegeben in V. Octane und G. Giuliani Piccari, L'opera di Anna Morandi Manzolini nella coroplastica bolognese, in Alma Mater Studiorum. La presenza femminile dal XVIII al XX secolo, Bologna 1988, S. 84. (Das Werk der Anna Morandi Manzolini in der Töpferkunst in Bologna, in: Alma Mater Studiorum. Die Präsenz von Frauen vom 18. bis zum 20. Jahrhundert), Public domain, https://commons.wikimedia.org/w/index.php?curid=1718618
1543 CE

Vesalius Publishes 'De Humani Corporis Fabrica'

Andreas Vesalius's groundbreaking work corrected many of Galen's errors, providing detailed illustrations of the brain and nervous system. He emphasized direct observation and dissection, revolutionizing anatomy. #neuroscience #history #anatomy

Vesalius Publishes 'De Humani Corporis Fabrica'
Vesalius Publishes 'De Humani Corporis Fabrica'
By Unknown author, Public domain, https://commons.wikimedia.org/w/index.php?curid=457251
1664 CE

Thomas Willis Publishes 'Cerebri Anatome'

English physician Thomas Willis coined the term 'neurology' and described the arterial circle at the base of the brain (Circle of Willis). He linked specific brain regions to functions like memory and emotion. #neuroscience #history #neurology

Thomas Willis Publishes 'Cerebri Anatome'
Thomas Willis Publishes 'Cerebri Anatome'
By David Loggan - http://www.oxforddnb.com/view/article/29587, Public domain, https://commons.wikimedia.org/w/index.php?curid=20313755
1791 CE

Luigi Galvani Discovers Animal Electricity

Italian physician Luigi Galvani demonstrated that frog leg muscles twitch when stimulated by electrical sparks, suggesting that nerves transmit electrical signals. This laid the foundation for electrophysiology. #neuroscience #history #electrophysiology

Luigi Galvani Discovers Animal Electricity
Luigi Galvani Discovers Animal Electricity
By Unidentified painter - http://www.museopalazzopoggi.unibo.it//poggi_eng/palazzo/foto/prot http://biografieonline.it/foto-di.htm?n=Luigi+Galvani, Public domain, https://commons.wikimedia.org/w/index.php?curid=2707375
1809 CE

Franz Joseph Gall Proposes Phrenology

German physician Franz Joseph Gall developed phrenology, the theory that mental faculties are localized in specific brain regions and that skull shape reflects personality. Though later discredited, it spurred research on brain localization. #neuroscience #history #phrenology

Franz Joseph Gall Proposes Phrenology
Franz Joseph Gall Proposes Phrenology
By Zéphirin Félix Jean Marius Belliard (1798–), engraver Delpech (Paris) - http://ihm.nlm.nih.gov/images/B12582, Public domain, https://commons.wikimedia.org/w/index.php?curid=19055991
1824 CE

Flourens Conducts Ablation Experiments on Animals

French physiologist Marie-Jean-Pierre Flourens used ablation techniques on animals to study brain function, concluding that the cerebellum coordinates movement and the medulla controls vital functions. He opposed phrenology. #neuroscience #history #experiment

Flourens Conducts Ablation Experiments on Animals
Flourens Conducts Ablation Experiments on Animals
By Unknown author, Public domain, https://commons.wikimedia.org/w/index.php?curid=1013650
1837 CE

Jan Purkinje Describes Purkinje Cells

Czech anatomist Jan Evangelista Purkinje identified large neurons in the cerebellar cortex, now known as Purkinje cells. He also described the Purkinje effect and contributed to histology. #neuroscience #history #histology

Jan Purkinje Describes Purkinje Cells
Jan Purkinje Describes Purkinje Cells
By Rudolph Hoffmann - This image is available from the United States Library of Congress's Prints and Photographs division under the digital ID cph.3c33404.This tag does not indicate the copyright status of the attached work. A normal copyright tag is still required. See Commons:Licensing., Public domain, https://commons.wikimedia.org/w/index.php?curid=3015732
1838 CE

Schwann and Schleiden Formulate Cell Theory

Theodor Schwann and Matthias Jakob Schleiden proposed that all living organisms are composed of cells. This theory later applied to the nervous system, leading to the understanding that neurons are the basic units. #neuroscience #history #biology

Schwann and Schleiden Formulate Cell Theory
Schwann and Schleiden Formulate Cell Theory
By TenOfAllTrades at English Wikipedia - Own work, Public domain, https://commons.wikimedia.org/w/index.php?curid=1583880
1848 CE

Phineas Gage Survives Severe Brain Injury

Railroad worker Phineas Gage survived an iron rod piercing his frontal lobe, resulting in profound personality changes. This case provided early evidence for the frontal lobe's role in personality and social behavior. #neuroscience #history #braininjury

Phineas Gage Survives Severe Brain Injury
Phineas Gage Survives Severe Brain Injury
By Photograph by Jack and Beverly Wilgus of daguerreotype originally from their collection, and now in the Warren Anatomical Museum, Center for the History of Medicine, Francis A. Countway Library of Medicine, Harvard Medical School.Enlarged using Waifu2x and retouched by Joe Haythornthwaite (see notes on talk page). - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=64865123
1861 CE

Broca Discovers Speech Center in the Brain

French surgeon Paul Broca examined a patient with speech impairment (Tan) and found a lesion in the left frontal lobe. He identified the region responsible for speech production, now known as Broca's area. #neuroscience #history #language

Broca Discovers Speech Center in the Brain
Broca Discovers Speech Center in the Brain
By Unknown author - Битнер В.В. На рубеже столетий: Обзор гл. науч. и культур. приобретений XIX века. 1901. URL:http://dlib.rsl.ru/view.php?path=/rsl01003000000/rsl01003963000/rsl01003963893/rsl01003963893.pdf#?page=451, Public domain, https://commons.wikimedia.org/w/index.php?curid=16545674
1870 CE

Fritsch and Hitzig Map Motor Cortex via Electrical Stimulation

German physicians Gustav Fritsch and Eduard Hitzig electrically stimulated the cerebral cortex of dogs, eliciting specific muscle movements. They demonstrated that motor functions are localized in the brain. #neuroscience #history #motorcortex

Fritsch and Hitzig Map Motor Cortex via Electrical Stimulation
Fritsch and Hitzig Map Motor Cortex via Electrical Stimulation
By Rudolf Dührkoop - [1], Public domain, https://commons.wikimedia.org/w/index.php?curid=57525502
1873 CE

Camillo Golgi Develops Silver Staining Method

Italian physician Camillo Golgi invented the silver nitrate staining technique (Golgi stain) that allowed visualization of individual neurons. This method revealed the complex structure of nerve cells. #neuroscience #history #histology

Camillo Golgi Develops Silver Staining Method
Camillo Golgi Develops Silver Staining Method
By Unknown author - [1] [2] [3], Public domain, https://commons.wikimedia.org/w/index.php?curid=18347448
1874 CE

Wernicke Identifies Language Comprehension Area

German neurologist Carl Wernicke described a region in the left temporal lobe (Wernicke's area) responsible for language comprehension. He proposed a model of language processing involving connections between brain areas. #neuroscience #history #language

Wernicke Identifies Language Comprehension Area
Wernicke Identifies Language Comprehension Area
By J.F. Lehmann, Muenchen - IHM, Public domain, https://commons.wikimedia.org/w/index.php?curid=9679254
1885 CE

Santiago Ramón y Cajal Applies Golgi Stain to Study Neurons

Spanish neuroscientist Santiago Ramón y Cajal used Golgi's stain to study the nervous system, proposing the neuron doctrine: that neurons are discrete cells that communicate via synapses. He is considered the father of modern neuroscience. #neuroscience #history #neurondoctrine

Santiago Ramón y Cajal Applies Golgi Stain to Study Neurons
Santiago Ramón y Cajal Applies Golgi Stain to Study Neurons
By Original photo is anonymous although published by Clark University in 1899. Restoration by Garrondo - Cajal.PNG, Public domain, https://commons.wikimedia.org/w/index.php?curid=12334552
1887 CE

Sherrington Coins the Term 'Synapse'

English physiologist Charles Scott Sherrington introduced the term 'synapse' to describe the junction between neurons. His work on reflex arcs and neural integration laid the foundation for understanding neural circuits. #neuroscience #history #synapse

Sherrington Coins the Term 'Synapse'
Sherrington Coins the Term 'Synapse'
By Unknown author - https://wellcomeimages.org/indexplus/image/L0014994.html, CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=33623905
1891 CE

Wilhelm von Waldeyer Coins 'Neuron'

German anatomist Wilhelm von Waldeyer-Hartz proposed the term 'neuron' to describe the nerve cell as the structural and functional unit of the nervous system, consolidating Cajal's neuron doctrine. #neuroscience #history #neuron

Wilhelm von Waldeyer Coins 'Neuron'
Wilhelm von Waldeyer Coins 'Neuron'
By Unknown author - http://ihm.nlm.nih.gov/images/B25498, Public domain, https://commons.wikimedia.org/w/index.php?curid=20366667
1898 CE

Golgi and Cajal Share Nobel Prize for Neuroscience

Camillo Golgi and Santiago Ramón y Cajal were jointly awarded the Nobel Prize in Physiology or Medicine for their work on the structure of the nervous system. Despite their differing views, their contributions were foundational. #neuroscience #history #Nobel

1906 CE

Alois Alzheimer Describes Alzheimer's Disease

German psychiatrist Alois Alzheimer presented a case of a woman with memory loss and brain abnormalities, including plaques and tangles. This became the first description of Alzheimer's disease. #neuroscience #history #Alzheimers

Alois Alzheimer Describes Alzheimer's Disease
Alois Alzheimer Describes Alzheimer's Disease
By Unknown author - Images from the History of Medicine (IHM), Public domain, https://commons.wikimedia.org/w/index.php?curid=11648572
1909 CE

Korbinian Brodmann Maps Brain Cytoarchitecture

German neurologist Korbinian Brodmann published a map of the cerebral cortex based on cell organization, identifying 52 distinct areas (Brodmann areas). This cytoarchitectonic map remains widely used today. #neuroscience #history #brainmapping

Korbinian Brodmann Maps Brain Cytoarchitecture
Korbinian Brodmann Maps Brain Cytoarchitecture
By Mark Dow. Research Assistant Brain Development Lab, University of Oregon. - http://lcni.uoregon.edu/~dow/Space_software/renderings.html, Public domain, https://commons.wikimedia.org/w/index.php?curid=8324220
1914 CE

Harvey Cushing Pioneers Modern Neurosurgery

American neurosurgeon Harvey Cushing developed techniques for brain tumor surgery, introduced the use of electrosurgery, and reduced mortality rates. He is considered the father of modern neurosurgery. #neuroscience #history #neurosurgery

Harvey Cushing Pioneers Modern Neurosurgery
Harvey Cushing Pioneers Modern Neurosurgery
By Unknown author - https://wellcomeimages.org/indexplus/image/V0027585.html This file comes from the Wellcome Collection, a website operated by Wellcome Trust, a global charitable foundation based in the United Kingdom. Refer to Wellcome blog post (archive).This tag does not indicate the copyright status of the attached work. A normal copyright tag is still required. See Commons:Licensing., CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=33621104
1924 CE

Hans Berger Records First Human Electroencephalogram (EEG)

German psychiatrist Hans Berger recorded the first human EEG, demonstrating electrical activity from the brain. He identified alpha and beta waves, opening the field of electroencephalography. #neuroscience #history #EEG

Hans Berger Records First Human Electroencephalogram (EEG)
Hans Berger Records First Human Electroencephalogram (EEG)
By Unknown author - http://www.psychiatrie.uk-j.de/Geschichte.html, Public domain, https://commons.wikimedia.org/w/index.php?curid=12160449
1932 CE

Sherrington and Adrian Win Nobel for Neuron Function

Charles Sherrington and Edgar Adrian shared the Nobel Prize for discoveries regarding the function of neurons, including the all-or-none law of nerve impulses and synaptic transmission. #neuroscience #history #Nobel

1937 CE

Papez Proposes Limbic System for Emotion

American anatomist James Papez described a neural circuit (Papez circuit) involving the hippocampus, thalamus, and cingulate cortex, proposing it as the basis for emotion. This laid groundwork for the limbic system concept. #neuroscience #history #emotion

Papez Proposes Limbic System for Emotion
Papez Proposes Limbic System for Emotion
By Original: teens.drugabuse.gov Vector: Pixelsquid🎱 - This file was derived from: Brain limbicsystem.jpg:, Public domain, https://commons.wikimedia.org/w/index.php?curid=99460976
1938 CE

Lorente de Nó Describes Recurrent Collateral Circuits

Spanish neuroscientist Rafael Lorente de Nó identified recurrent collateral circuits in the hippocampus, contributing to the understanding of neural networks and memory formation. #neuroscience #history #neuralcircuits

1943 CE

McCulloch and Pitts Propose Neural Network Model

Warren McCulloch and Walter Pitts published a mathematical model of artificial neurons, showing that simple neural networks could perform logical operations. This work laid the foundation for artificial neural networks and computational neuroscience. #neuroscience #history #AI

McCulloch and Pitts Propose Neural Network Model
McCulloch and Pitts Propose Neural Network Model
By Funcs - Own work, CC0, https://commons.wikimedia.org/w/index.php?curid=148910507
1949 CE

Donald Hebb Proposes Hebbian Learning Rule

Canadian psychologist Donald Hebb published 'The Organization of Behavior,' proposing that neurons that fire together wire together (Hebbian theory). This principle became fundamental for understanding synaptic plasticity and learning. #neuroscience #history #plasticity

Donald Hebb Proposes Hebbian Learning Rule
Donald Hebb Proposes Hebbian Learning Rule
By Henry Vandyke Carter - Henry Gray (1918) Anatomy of the Human Body (See "Book" section below) Bartleby.com: Gray's Anatomy, Plate 728 This is a retouched picture, which means that it has been digitally altered from its original version. Modifications: vectorization (CorelDraw). The original can be viewed here: Gray728.png: . Modifications made by Mysid., Public domain, https://commons.wikimedia.org/w/index.php?curid=1676555
1950 CE

Alan Hodgkin and Andrew Huxley Describe Action Potential

British physiologists Alan Hodgkin and Andrew Huxley used the squid giant axon to describe the ionic mechanisms underlying the action potential. Their model earned them the Nobel Prize and is a cornerstone of neurophysiology. #neuroscience #history #actionpotential

Alan Hodgkin and Andrew Huxley Describe Action Potential
Alan Hodgkin and Andrew Huxley Describe Action Potential
By Krishnavedala - Own work, CC0, https://commons.wikimedia.org/w/index.php?curid=21725464
1952 CE

First Successful Human Deep Brain Stimulation

Neurosurgeons performed the first deep brain stimulation (DBS) in humans to treat movement disorders. DBS later became a key therapy for Parkinson's disease and other conditions. #neuroscience #history #DBS

First Successful Human Deep Brain Stimulation
First Successful Human Deep Brain Stimulation
By Hellerhoff - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=13785677
1953 CE

Patient HM Undergoes Temporal Lobe Surgery

Henry Molaison (Patient HM) had bilateral medial temporal lobe resection to treat epilepsy, resulting in severe anterograde amnesia. His case revealed the critical role of the hippocampus in forming new memories. #neuroscience #history #memory

1957 CE

Vernon Mountcastle Discovers Cortical Columns

American neuroscientist Vernon Mountcastle identified columnar organization in the somatosensory cortex, where neurons with similar properties are arranged vertically. This concept became a fundamental principle of cortical organization. #neuroscience #history #cortex

1960 CE

Hubel and Wiesel Discover Orientation Columns in Visual Cortex

David Hubel and Torsten Wiesel used single-unit recording in cats to show that neurons in the visual cortex respond to specific orientations. Their work on visual processing earned them a Nobel Prize. #neuroscience #history #vision

Hubel and Wiesel Discover Orientation Columns in Visual Cortex
Hubel and Wiesel Discover Orientation Columns in Visual Cortex
By Joey cantod - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=79369186
1963 CE

Eccles, Hodgkin, and Huxley Win Nobel for Synaptic Transmission

John Eccles shared the Nobel Prize with Hodgkin and Huxley for his work on synaptic transmission, particularly the role of ions in excitatory and inhibitory postsynaptic potentials. #neuroscience #history #Nobel

Eccles, Hodgkin, and Huxley Win Nobel for Synaptic Transmission
Eccles, Hodgkin, and Huxley Win Nobel for Synaptic Transmission
By Unknown author - https://wellcomeimages.org/indexplus/obf_images/42/86/2e1a4ca2e1c91a1f5aa88c6db04d.jpg Gallery: https://wellcomeimages.org/indexplus/image/L0026812.html, CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=36013687
1966 CE

Paul MacLean Proposes Triune Brain Model

American physician Paul MacLean introduced the triune brain model, dividing the brain into reptilian, limbic, and neocortex layers. Though later criticized, it popularized the idea of brain evolution. #neuroscience #history #evolution

Paul MacLean Proposes Triune Brain Model
Paul MacLean Proposes Triune Brain Model
By Lchunhori at English Wikipedia - Own work by the original uploader, CC BY-SA 2.5, https://commons.wikimedia.org/w/index.php?curid=42657486
1970 CE

First CT Scan of the Brain

Godfrey Hounsfield and Allan Cormack developed computed tomography (CT), enabling non-invasive imaging of the brain. CT scans revolutionized diagnosis of brain tumors, hemorrhages, and structural abnormalities. #neuroscience #history #imaging

First CT Scan of the Brain
First CT Scan of the Brain
By Food and Drug Administration - https://fda.gov/radiation-emitting-products/medical-x-ray-imaging/computed-tomography-ct, Public domain, https://commons.wikimedia.org/w/index.php?curid=99627315
1973 CE

Paul Lauterbur Develops MRI

American chemist Paul Lauterbur produced the first magnetic resonance image (MRI) of a living organism. MRI later became a crucial tool for brain imaging, providing detailed soft tissue contrast. #neuroscience #history #MRI

Paul Lauterbur Develops MRI
Paul Lauterbur Develops MRI
By Bush6NobelLaureates.jpg: Tina Hager derivative work: Elinnea (talk) - Bush6NobelLaureates.jpg, Public domain, https://commons.wikimedia.org/w/index.php?curid=16855696
1976 CE

Seiji Ogawa Discovers BOLD Signal for fMRI

Japanese physicist Seiji Ogawa identified the blood-oxygen-level-dependent (BOLD) contrast mechanism, which became the basis for functional MRI (fMRI). This allowed mapping of brain activity non-invasively. #neuroscience #history #fMRI

Seiji Ogawa Discovers BOLD Signal for fMRI
Seiji Ogawa Discovers BOLD Signal for fMRI
By Rickinasia - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=83027417
1980 CE

First Human Brain PET Scan

Positron emission tomography (PET) was first used to image human brain metabolism and neurotransmitter activity. PET scans enabled studies of brain function in health and disease. #neuroscience #history #PET

First Human Brain PET Scan
First Human Brain PET Scan
By Spacecoastcreative - Own work, CC0, https://commons.wikimedia.org/w/index.php?curid=149063982
1981 CE

Hubel and Wiesel Win Nobel for Visual System

David Hubel and Torsten Wiesel received the Nobel Prize for their discoveries about information processing in the visual system, including orientation columns and binocular vision. #neuroscience #history #Nobel

1986 CE

Eric Kandel Identifies Molecular Basis of Memory in Aplysia

Austrian-born American neuroscientist Eric Kandel used the sea slug Aplysia to study the molecular mechanisms of learning and memory, discovering the role of protein synthesis in long-term potentiation. #neuroscience #history #memory

Eric Kandel Identifies Molecular Basis of Memory in Aplysia
Eric Kandel Identifies Molecular Basis of Memory in Aplysia
By Bengt Oberger - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=37241660
1990 CE

Human Genome Project Launched

The Human Genome Project began, aiming to sequence the entire human genome. This project later provided insights into genetic factors influencing brain development, function, and neurological disorders. #neuroscience #history #genetics

Human Genome Project Launched
Human Genome Project Launched
By U.S. Department of Energy, Human Genome Project - http://www.ornl.gov/hgmis, Public domain, https://commons.wikimedia.org/w/index.php?curid=2485616
1991 CE

First Functional MRI (fMRI) of Human Brain

Researchers performed the first fMRI scans of the human brain using BOLD contrast, demonstrating that brain activity could be mapped non-invasively. fMRI became a dominant tool in cognitive neuroscience. #neuroscience #history #fMRI

First Functional MRI (fMRI) of Human Brain
First Functional MRI (fMRI) of Human Brain
By OpenStax - https://openstax.org/books/anatomy-and-physiology/pages/12-1-basic-structure-and-function-of-the-nervous-system, CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=30147912
1997 CE

Deep Brain Stimulation Approved for Parkinson's

The U.S. FDA approved deep brain stimulation (DBS) for treating essential tremor and Parkinson's disease. DBS involves implanting electrodes in specific brain regions to modulate abnormal neural activity. #neuroscience #history #Parkinsons

2000 CE

Arvid Carlsson, Paul Greengard, Eric Kandel Win Nobel for Signal Transduction

The Nobel Prize was awarded for discoveries concerning signal transduction in the nervous system, including dopamine's role in Parkinson's and molecular mechanisms of memory. #neuroscience #history #Nobel