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Linus Pauling: Nature of the Chemical Bond, Alpha Helix & Dual Nobel Laureate

Encyclopedia/1. The Cosmos & The Natural World/2. Physics & Chemistry/13. Physical & Chemical Biographies  •  Curated by Admin Timeline.sg

Historical events timeline.

Chronological Storyline (41 Milestones)

Feb 28, 1901 CE

Linus Pauling Born in Portland, Oregon

Linus Carl Pauling is born to Herman Henry William Pauling and Lucy Isabelle Darling in Portland, Oregon. #chemistry #biography

Linus Pauling Born in Portland, Oregon
Linus Pauling Born in Portland, Oregon
By Unknown author - Oregon State University [1], CC BY-SA 2.0, https://commons.wikimedia.org/w/index.php?curid=144490366
Jun 1, 1910 CE

Father Dies, Leaving Family in Financial Strait

Pauling's father dies, leaving his mother to raise Linus and his two sisters. Pauling takes on odd jobs to help support the family. #biography

Sep 1, 1917 CE

Enters Oregon Agricultural College (OAC)

Pauling enrolls at Oregon Agricultural College (now Oregon State University) to study chemical engineering. He works to pay his way through college. #education #chemistry

Jun 1, 1922 CE

Graduates from OAC with Bachelor's in Chemical Engineering

Pauling graduates with a degree in chemical engineering. He then pursues graduate studies at the California Institute of Technology (Caltech). #education #chemistry

Jun 17, 1923 CE

Marries Ava Helen Miller

Pauling marries Ava Helen Miller, who later becomes a prominent peace activist and influences his political work. #biography

Marries Ava Helen Miller
Marries Ava Helen Miller
By Unknown author, PD-US, https://en.wikipedia.org/w/index.php?curid=14811760
Jun 1, 1925 CE

Receives Ph.D. in Chemistry from Caltech

Pauling earns his Ph.D. with a thesis on the structure of crystals using X-ray diffraction, under the supervision of Roscoe G. Dickinson. #chemistry #education

1926 CE

Guggenheim Fellowship in Europe

Pauling receives a Guggenheim Fellowship to study in Europe, working with Arnold Sommerfeld in Munich, Erwin Schrödinger in Zurich, and Niels Bohr in Copenhagen. #science #chemistry

1927 CE

Returns to Caltech as Assistant Professor

After his European tour, Pauling joins the Caltech faculty as an assistant professor of theoretical chemistry. #chemistry #biography

1928 CE

Introduces the Concept of Hybridization

Pauling develops the theory of orbital hybridization to explain the geometry of chemical bonds, such as in methane. #chemistry #quantum

1931 CE

Publishes Paper on Electronegativity

Pauling introduces the concept of electronegativity and develops a scale (Pauling scale) to quantify the tendency of atoms to attract electrons. #chemistry #electronegativity

1931 CE

Awarded the Langmuir Prize

Pauling receives the American Chemical Society's Langmuir Prize as the nation's most promising young chemist. #chemistry #award

1932 CE

Elected to the National Academy of Sciences

At age 31, Pauling is elected to the National Academy of Sciences, one of the youngest ever. #chemistry #honors

Elected to the National Academy of Sciences
Elected to the National Academy of Sciences
By Túrelio - Own work, CC BY-SA 2.5, https://commons.wikimedia.org/w/index.php?curid=1944414
1933 CE

Publishes Fundamental Work on Resonance Theory

Pauling extends Lewis's bonding theory with resonance structures, explaining the properties of molecules like benzene. #chemistry #quantum )

1936 CE

Becomes Chairman of the Chemistry Division at Caltech

Pauling is appointed chairman of the Division of Chemistry and Chemical Engineering at Caltech. #chemistry #academia

1939 CE

Publishes 'The Nature of the Chemical Bond'

Pauling's seminal book 'The Nature of the Chemical Bond and the Structure of Molecules and Crystals' is published, summarizing his groundbreaking work. #chemistry #book

1940 CE

Applies Resonance Theory to Antibodies

Pauling proposes a theory of antibody formation based on molecular complementarity, influencing immunology. #chemistry #biology

1941 CE

Diagnosed with Glomerulonephritis

Pauling is diagnosed with a serious kidney disease; he adopts a low-protein diet and later experiments with vitamin C. #biography #health

1944 CE

Develops a Substitute for Blood Plasma

During World War II, Pauling develops a synthetic plasma substitute using gelatin, saving many lives. #chemistry #medicine

1948 CE

Receives the Presidential Medal for Merit

Pauling is awarded the Presidential Medal for Merit by President Truman for his wartime contributions. #honors #chemistry

Receives the Presidential Medal for Merit
Receives the Presidential Medal for Merit
By Unknown author - API data Catalogue record Photo, CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=65639617
1949 CE

First Accurate Model of Hemoglobin Structure

Pauling and his colleagues discover that sickle cell anemia is caused by an abnormal hemoglobin molecule (molecular disease concept). #chemistry #biology

First Accurate Model of Hemoglobin Structure
First Accurate Model of Hemoglobin Structure
By The National Heart, Lung, and Blood Institute (NHLBI) - http://www.nhlbi.nih.gov/health/health-topics/topics/sca/, Public domain, https://commons.wikimedia.org/w/index.php?curid=19198765
Apr 1, 1951 CE

Discovers the Alpha Helix Structure of Proteins

Pauling and Robert Corey propose the alpha helix and beta sheet as the two principal protein secondary structures. #chemistry #biology

Discovers the Alpha Helix Structure of Proteins
Discovers the Alpha Helix Structure of Proteins
By Theislikerice - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=81729199
1952 CE

Denied Passport Due to Political Views

Pauling is denied a passport by the U.S. State Department for his anti-war activism, limiting his ability to travel. #activism #politics

Nov 3, 1954 CE

Awarded the Nobel Prize in Chemistry

Pauling receives the Nobel Prize in Chemistry 'for his research into the nature of the chemical bond and its application to the elucidation of the structure of complex substances.' #nobel #chemistry

1955 CE

Signs the Mainau Declaration Against Nuclear Weapons

Pauling joins other Nobel laureates in signing the Mainau Declaration, warning of the dangers of nuclear weapons. #activism #peace

Jan 15, 1958 CE

Presents UN Petition Against Nuclear Testing

Pauling submits a petition signed by 11,021 scientists from 49 countries to the United Nations calling for an end to nuclear weapons testing. #activism #nuclear

Oct 1, 1958 CE

Publishes 'No More War!'

Pauling's book 'No More War!' outlines the dangers of nuclear fallout and calls for disarmament. #activism #book

1961 CE

Begins Advocacy for Vitamin C in Preventing Colds

Pauling becomes interested in the potential health benefits of high-dose vitamin C, later sparking a controversy. #health #medicine

Oct 10, 1962 CE

Awarded the Nobel Peace Prize

Pauling receives the Nobel Peace Prize for his efforts to ban nuclear weapons testing. He is the only person to win two unshared Nobel Prizes. #nobel #peace

1963 CE

Resigns from Caltech After Political Controversy

Pauling resigns from Caltech due to conflicts over his political activism and reduced scientific productivity. #academia #activism

1964 CE

Joins the Center for the Study of Democratic Institutions

Pauling takes a position at the Center for the Study of Democratic Institutions in Santa Barbara, California. #activism #biography

1967 CE

Joins University of California, San Diego

Pauling becomes a professor of chemistry at UC San Diego. #chemistry #academia

Joins University of California, San Diego
Joins University of California, San Diego
By Tiffany & Co. - Own work using: http://ucpa.ucsd.edu/images/uploads/ucsandiego-brandguidelines-2016-09-26.pdf, Public domain, https://commons.wikimedia.org/w/index.php?curid=133150753
1969 CE

Moves to Stanford University

Pauling joins Stanford University as a professor of chemistry. #chemistry #academia

Moves to Stanford University
Moves to Stanford University
By Arthur Bridgeman Clark - https://i.pinimg.com/736x/02/9b/45/029b45d5b77a2d9d45028c6c77fadbdd.jpg, Public domain, https://commons.wikimedia.org/w/index.php?curid=132437709
1970 CE

Publishes 'Vitamin C and the Common Cold'

Pauling's book promoting high-dose vitamin C for preventing and treating the common cold becomes a bestseller and sparks widespread debate. #health #medicine

1973 CE

Founds the Linus Pauling Institute of Science and Medicine

Pauling establishes the institute in Palo Alto, California, to continue his research on vitamin C and health. #research #health

Founds the Linus Pauling Institute of Science and Medicine
Founds the Linus Pauling Institute of Science and Medicine
By JABurlock - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=163350169
1975 CE

Retires from Stanford but Continues Research

Pauling becomes Professor Emeritus at Stanford but remains active as director of the Linus Pauling Institute. #biography #academia

1979 CE

Publishes 'Cancer and Vitamin C' with Ewan Cameron

Pauling and Cameron claim that high-dose vitamin C extends survival in terminal cancer patients, a controversial assertion. #health #cancer

1981 CE

Receives the Lomonosov Gold Medal

Pauling is awarded the Lomonosov Gold Medal by the USSR Academy of Sciences for his contributions to chemistry. #honors #chemistry

Receives the Lomonosov Gold Medal
Receives the Lomonosov Gold Medal
By Sergey Konenkov - Oficial web-site of the Russian Academy of Sciences, Public domain, https://commons.wikimedia.org/w/index.php?curid=21423934
1984 CE

Receives the Priestley Medal

Pauling receives the American Chemical Society's highest honor, the Priestley Medal. #chemistry #honors

1986 CE

Ava Helen Pauling Dies

Pauling's wife of 63 years, Ava Helen, dies. Her death deeply affects him. #biography

1987 CE

Published Papers on Orthomolecular Medicine

Pauling continues to advocate for orthomolecular medicine, focusing on the use of nutrients to treat disease. #health #medicine

1991 CE

Diagnosed with Prostate Cancer

Pauling is diagnosed with prostate cancer and treats himself with high-dose vitamins. #health #biography