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Hippocrates of Kos: Father of Medicine, Hippocratic Oath & Humoral Theory

Encyclopedia/1. The Cosmos & The Natural World/6. Medicine & Human Biology/07. Medical & Health Biographies  •  Curated by Admin Timeline.sg

Hippocrates of Kos, born around 460 BCE, revolutionized medicine by separating it from superstition and religious dogma, establishing clinical observation and the humoral theory. His Hippocratic Oath remains a cornerstone of medical ethics.

Chronological Storyline (40 Milestones)

460 BCE

Birth of Hippocrates on Kos

Hippocrates is born on the Greek island of Kos to Heraclides and Praxitela, probably into a family of physicians. #medicine #history

Birth of Hippocrates on Kos
Birth of Hippocrates on Kos
By Unidentified engraver - 1881 Young Persons' Cyclopedia of Persons and Places Upload by RedWolf 05:45, Jan 10, 2005 (UTC), Public domain, https://commons.wikimedia.org/w/index.php?curid=164808
450 BCE

Early Education by Father and Teachers

Hippocrates receives early education in medicine and philosophy from his father Heraclides and other local teachers on Kos. #medicine #history

440 BCE

Training at the Asklepieion of Kos

Hippocrates trains at the Asklepieion of Kos, a healing temple dedicated to Asclepius, where he learns practical medicine and the traditions of the Asclepiads. #medicine #history

Training at the Asklepieion of Kos
Training at the Asklepieion of Kos
By Unknown author, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=81874
430 BCE

Begins Teaching Medicine on Kos

Hippocrates starts teaching medicine on Kos, establishing a school that emphasizes systematic clinical observation and rational diagnosis. #medicine #history

425 BCE

Rejection of Divine Causes of Disease (On the Sacred Disease)

Hippocrates writes 'On the Sacred Disease', arguing that epilepsy is not divine punishment but a natural brain disorder, marking a departure from supernatural explanations. #medicine #history

420 BCE

Formulation of the Four Humors Theory

Hippocrates, possibly in 'On the Nature of Man', formalizes the humoral theory: health depends on balance of blood, phlegm, yellow bile, and black bile. #medicine #history

Formulation of the Four Humors Theory
Formulation of the Four Humors Theory
By Unknown author - https://www.arsgravis.com/UserFiles/image/Andrigino_NOU/androgino7.jpg, Public domain, https://commons.wikimedia.org/w/index.php?curid=27729929
415 BCE

Composition of Aphorisms

Hippocrates writes 'Aphorisms', a collection of concise medical axioms, including the famous opening line 'Life is short, art long'. #medicine #history

410 BCE

Writing of On Airs, Waters, Places

Hippocrates writes 'On Airs, Waters, Places', emphasizing environmental factors in disease and establishing the foundations of epidemiology and medical geography. #medicine #history

405 BCE

Development of Clinical Prognosis (Prognostics)

Hippocrates writes 'Prognostics', detailing methods for predicting disease outcomes based on observation of symptoms and vital signs. #medicine #history

400 BCE

Composition of the Hippocratic Oath

The Hippocratic Oath, attributed to Hippocrates, is composed, defining ethical duties of physicians including confidentiality and non-maleficence. #medicine #ethics

395 BCE

Writing of On Fractures and On Joints

Hippocrates writes treatises on orthopedics, describing techniques for reducing fractures and dislocations, including the use of the Hippocratic bench. #medicine #surgery

390 BCE

Treats Perdiccas II of Macedon (Love Sickness)

Legend holds that Hippocrates diagnoses Perdiccas II of Macedon with lovesickness, demonstrating psychosomatic understanding. #medicine #history

385 BCE

Travels to Thessaly and Thrace

Hippocrates travels extensively through Thessaly, Thrace, and other regions, practicing and teaching medicine, spreading his methods. #medicine #history

380 BCE

Disagreement with the Cnidian School of Medicine

Hippocrates criticizes the Cnidian school's over-reliance on classification and specifics, advocating for holistic observation and general principles. #medicine #history

375 BCE

Writing of On the Nature of Man

Hippocrates or his son-in-law Polybus writes 'On the Nature of Man', which elaborates the four humors and their seasonal variations. #medicine #history

370 BCE

Death of Hippocrates in Larissa

Hippocrates dies in Larissa, Thessaly, at an advanced age (around 90). His legacy endures through his writings and ethical standards. #medicine #history

350 BCE

Compilation of the Hippocratic Corpus Begins

Following Hippocrates' death, his followers and later scholars compile his works and those of his school into the 'Hippocratic Corpus' at the Library of Alexandria. #medicine #history

300 BCE

Influence on Hellenistic Medicine: Herophilus and Erasistratus

Herophilus and Erasistratus of Alexandria, pioneers of anatomy, build upon Hippocratic observational methods, though they perform dissection. #medicine #history

Influence on Hellenistic Medicine: Herophilus and Erasistratus
Influence on Hellenistic Medicine: Herophilus and Erasistratus
By Ecelan - Own work, CC BY-SA 3.0 es, https://commons.wikimedia.org/w/index.php?curid=16641053
200 BCE

Influence on Roman Medicine: Cato the Elder

Roman writers like Cato the Elder reference Hippocrates, though often critically, as Greek medicine spreads to Rome. #medicine #history

129 CE

Galen of Pergamon Studies Hippocratic Works

Galen, the most influential physician after Hippocrates, studies and extensively comments on Hippocratic writings, integrating humoral theory into his own system. #medicine #history

Galen of Pergamon Studies Hippocratic Works
Galen of Pergamon Studies Hippocratic Works
By Georg Paul Busch (engraver) - The Lancet, Public domain, https://commons.wikimedia.org/w/index.php?curid=40855568
500 CE

Translation into Syriac and Arabic

Hippocratic works are translated into Syriac and Arabic by Nestorian Christians and later by Muslim scholars, preserving them during the Middle Ages. #medicine #history

Translation into Syriac and Arabic
Translation into Syriac and Arabic
By Arabischer Maler des Kräuterbuchs des Dioskurides - The Yorck Project (2002) 10.000 Meisterwerke der Malerei (DVD-ROM), distributed by DIRECTMEDIA Publishing GmbH. ISBN: 3936122202., Public domain, https://commons.wikimedia.org/w/index.php?curid=147655
900 CE

Al-Razi (Rhazes) Comments on Hippocrates

Persian physician Al-Razi writes commentaries on Hippocrates, integrating his ideas into Islamic medicine. #medicine #history

1100 CE

Translation into Latin by Constantine the African

Constantinus Africanus translates Hippocratic texts from Arabic into Latin at the Schola Medica Salernitana, reintroducing them to Europe. #medicine #history

Translation into Latin by Constantine the African
Translation into Latin by Constantine the African
By Unknown artist - muslimisches Erbe : Galerie ° Info ° Pic; https://digital.bodleian.ox.ac.uk/inquire/p/2a16dc40-fc18-47db-8fda-48ffc9e79abe, Public domain, https://commons.wikimedia.org/w/index.php?curid=1718587
1400 CE

Renaissance Humanism Revives Hippocratic Medicine

During the Renaissance, humanist scholars return to original Greek texts of Hippocrates, leading to a renewed emphasis on direct observation. #medicine #history

1525 CE

First Printed Edition of Hippocratic Works

The first printed edition of the Hippocratic Corpus is published in Rome, making his works widely accessible to physicians. #medicine #history

1600 CE

William Harvey and Humoral Theory

William Harvey's discovery of blood circulation challenges humoral theory, but Hippocratic clinical methods remain influential. #medicine #history

William Harvey and Humoral Theory
William Harvey and Humoral Theory
By After Daniël Mijtens - National Portrait Gallery: NPG 5115, Public domain, https://commons.wikimedia.org/w/index.php?curid=5975113
1800 CE

Modern Medicine Begins to Shift from Humoral Theory

Advances in pathophysiology and germ theory gradually replace humoral theory, but Hippocrates' emphasis on observation and ethics persists. #medicine #history

1847 CE

American Medical Association Adopts Hippocratic Oath

The newly formed American Medical Association adopts a code of ethics based on the Hippocratic Oath, standardizing medical ethics in the US. #medicine #ethics

1910 CE

Flexner Report Cites Hippocratic Ideals

The Flexner Report on medical education in the US cites Hippocratic ideals of scientific rigor and ethics, influencing reforms. #medicine #history

Flexner Report Cites Hippocratic Ideals
Flexner Report Cites Hippocratic Ideals
By Creator:Abraham Flexner - http://www.carnegiefoundation.org/sites/default/files/elibrary/Carnegie_Flexner_Report.pdf, Public domain, https://commons.wikimedia.org/w/index.php?curid=51763611
1928 CE

Discovery of the Hippocratic Face (Facies Hippocratica)

The 'Hippocratic face' described by Hippocrates is identified as a sign of impending death in acutely ill patients. #medicine #history

Discovery of the Hippocratic Face (Facies Hippocratica)
Discovery of the Hippocratic Face (Facies Hippocratica)
By Rosemary A Jones - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=50645958
1948 CE

World Medical Association Adopts Declaration of Geneva

The WMA adopts the Declaration of Geneva, a modernized version of the Hippocratic Oath, as a standard for physicians worldwide. #medicine #ethics

1959 CE

Excavation of the Asklepieion on Kos

Archaeological excavations on Kos uncover the Asklepieion, where Hippocrates likely taught, revealing ancient medical facilities. #archaeology #medicine

1974 CE

Hippocrates Bust Discovered?

A marble bust of Hippocrates is discovered on Kos, now displayed in the Kos Archaeological Museum. #archaeology #medicine

1993 CE

Hippocrates.org Launched

The website Hippocrates.org is launched, providing resources on Hippocratic medicine and the history of medicine. #medicine #history

2002 CE

Hippocrates Prize for Poetry and Medicine

The Hippocrates Prize is established to encourage engagement between medicine and poetry, honoring the holistic tradition. #medicine #literature

2010 CE

UNESCO Recognition of Hippocratic Oath

The Hippocratic Oath is inscribed in UNESCO's Memory of the World Register as a document of universal ethical value. #medicine #ethics

2014 CE

Hippocrates of Kos: Father of Medicine Exhibition

A major exhibition on Hippocrates is held at the National Archaeological Museum of Athens, showcasing artifacts and texts. #medicine #history

2019 CE

New Evidence on Hippocrates' Birth Year

Scholars propose a revised birth year for Hippocrates based on ancient sources, suggesting 460 BCE remains most likely. #medicine #history

2021 CE

Hippocratic Oath Ceremony at Medical Graduations Worldwide

Modern medical schools continue to hold Hippocratic Oath ceremonies, adapting the oath to contemporary values. #medicine #ethics

2023 CE

Hippocrates Digital Archive Project

A digital archive of all Hippocratic texts is launched by the Wellcome Library, making them freely accessible online. #medicine #history