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Chemistry & Periodic Law: Chinese Alchemy to Lavoisier & Mendeleev

Encyclopedia/1. The Cosmos & The Natural World/2. Physics & Chemistry/03. Chemistry & Periodic Table of Elements  •  Curated by Admin Timeline.sg

The history of chemistry spans from ancient Chinese alchemy and the Five Elements theory to Lavoisier's oxygen theory, Dalton's atomic weights, Mendeleev's periodic table, and modern quantum chemistry. This timeline highlights key milestones in the transformation of matter understanding across global cultures.

Chronological Storyline (49 Milestones)

500 BCE

Chinese Wuxing Theory Developed

The Chinese Five Elements (Wuxing) theory—wood, fire, earth, metal, water—emerges as a philosophical framework for natural processes, influencing early alchemy and medicine. #chemistry #history )

Chinese Wuxing Theory Developed
Chinese Wuxing Theory Developed
By Jim McKeeth - Own work based on old version, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=163156799
400 BCE

Democritus Proposes Atomism

Greek philosopher Democritus proposes that matter consists of indivisible particles called atoms, laying a conceptual foundation for atomic theory. #chemistry #philosophy

Democritus Proposes Atomism
Democritus Proposes Atomism
By user:shakko - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=5535206
350 BCE

Aristotle's Four Elements

Aristotle formalizes the four-element theory (earth, water, air, fire), which dominates Western thought for nearly two millennia. #chemistry #philosophy

Aristotle's Four Elements
Aristotle's Four Elements
By Gottfried Wilhelm von Leibniz - Dissertatio de Arte Combinatoria, Public domain, https://commons.wikimedia.org/w/index.php?curid=39729133
300 CE

Chinese Alchemy: Ge Hong's Baopuzi

Ge Hong writes the Baopuzi, a key alchemical text describing elixirs for immortality and the transformation of cinnabar. #chemistry #alchemy

Chinese Alchemy: Ge Hong's Baopuzi
Chinese Alchemy: Ge Hong's Baopuzi
By Gan Bozong (Tang period, 618-907) - https://wellcomeimages.org/indexplus/obf_images/5f/87/4e750c334bb041db425934535c34.jpg (hi-res image) Gallery: https://wellcomeimages.org/indexplus/image/L0039323.html Wellcome Collection gallery (2018-03-28): https://wellcomecollection.org/works/f65bzfbc CC-BY-4.0, CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=33926771
800 CE

Jabir ibn Hayyan's Alchemical Works

Jabir ibn Hayyan (Geber) pioneers experimental chemistry, discovering acids like hydrochloric and nitric acid, and developing distillation and crystallization techniques. #chemistry #alchemy

Jabir ibn Hayyan's Alchemical Works
Jabir ibn Hayyan's Alchemical Works
By Unknown author - https://cdn.britannica.com/10/132710-050-CECF006B/illustration-manuscript-Abu-Musa-Jabir-ibn-Hayyan.jpg, Public domain, https://commons.wikimedia.org/w/index.php?curid=166835469
1000 CE

Al-Razi's Chemical Classifications

Persian physician Al-Razi (Rhazes) classifies substances into animal, vegetable, and mineral categories, and describes chemical processes like distillation. #chemistry #medicine

1250 CE

Albertus Magnus on Alchemy

Albertus Magnus writes extensively on alchemy, describing the composition of metals and the philosopher's stone, influencing European alchemy. #chemistry #alchemy

Albertus Magnus on Alchemy
Albertus Magnus on Alchemy
By Vicente Salvador Gómez - [2], Public domain, https://commons.wikimedia.org/w/index.php?curid=8528799
1597 CE

Andreas Libavius Publishes Alchemia

Libavius publishes Alchemia, one of the first chemistry textbooks, systematically describing chemical preparations and apparatus. #chemistry #history

Andreas Libavius Publishes Alchemia
Andreas Libavius Publishes Alchemia
By Unknown author - Unknown source, Public domain, https://commons.wikimedia.org/w/index.php?curid=8949023
1661 CE

Robert Boyle's The Sceptical Chymist

Boyle defines elements as simple substances and argues for experimental chemistry, breaking from alchemical traditions. #chemistry #science

Robert Boyle's The Sceptical Chymist
Robert Boyle's The Sceptical Chymist
By Robert Boyle, 1627-1691 - Science History Institute, Public domain, https://commons.wikimedia.org/w/index.php?curid=26729105
1669 CE

Hennig Brand Discovers Phosphorus

Brand isolates phosphorus from urine, the first element discovery documented in modern chemistry. #chemistry #discovery

Hennig Brand Discovers Phosphorus
Hennig Brand Discovers Phosphorus
By Joseph Wright of Derby - http://www.tms.org/pubs/journals/JOM/0706/fig3.jpg http://www.culturevoyage.co.uk/wp-content/uploads/2013/03/Alchymist.jpg, Public domain, https://commons.wikimedia.org/w/index.php?curid=15154197
1703 CE

Georg Stahl's Phlogiston Theory

Stahl proposes phlogiston theory to explain combustion, a dominant paradigm until Lavoisier. #chemistry #history

Georg Stahl's Phlogiston Theory
Georg Stahl's Phlogiston Theory
By Wolfgang Philipp Kilian - This image has been extracted from another file, Public domain, https://commons.wikimedia.org/w/index.php?curid=5722070
1735 CE

Brandt Isolates Cobalt

Swedish chemist Georg Brandt discovers and isolates cobalt, the first metal discovered since antiquity. #chemistry #discovery

1746 CE

Roebuck's Lead Chamber Process

John Roebuck invents the lead chamber process for producing sulfuric acid on an industrial scale, advancing chemical manufacturing. #chemistry #industry

1754 CE

Black Discovers Carbon Dioxide

Joseph Black identifies carbon dioxide (fixed air) through experiments on limestone, distinguishing it from air. #chemistry #discovery

Black Discovers Carbon Dioxide
Black Discovers Carbon Dioxide
By Rogers, J - http://ihm.nlm.nih.gov/images/B02979, Public domain, https://commons.wikimedia.org/w/index.php?curid=19132802
1766 CE

Cavendish Discovers Hydrogen

Henry Cavendish isolates hydrogen (inflammable air) and measures its density, paving the way for understanding gases. #chemistry #discovery

Cavendish Discovers Hydrogen
Cavendish Discovers Hydrogen
By George Wilson - Frontispiece of The Life of the Hon. Henry Cavendish, Public domain, https://commons.wikimedia.org/w/index.php?curid=7373371
1774 CE

Priestley Discovers Oxygen

Joseph Priestley isolates oxygen (dephlogisticated air) and notes its support of combustion and respiration. #chemistry #discovery

Priestley Discovers Oxygen
Priestley Discovers Oxygen
By James Sharples - https://npg.si.edu/object/npg_NPG.77.160?destination=node/63231%3Fedan_local%3D1%26edan_q%3DJoseph, Public domain, https://commons.wikimedia.org/w/index.php?curid=193629762
1777 CE

Lavoisier's Oxygen Theory of Combustion

Antoine Lavoisier publishes his oxygen theory, refuting phlogiston and establishing modern chemistry with mass conservation. #chemistry #science

Lavoisier's Oxygen Theory of Combustion
Lavoisier's Oxygen Theory of Combustion
By Jacques-Louis David - Metropolitan Museum of Art: entry 436106 (accession number: 1977.10), Public domain, https://commons.wikimedia.org/w/index.php?curid=141652400
1789 CE

Lavoisier's Traité Élémentaire de Chimie

Lavoisier publishes the first modern chemistry textbook, listing 33 elements and defining the law of conservation of mass. #chemistry #textbook

Lavoisier's Traité Élémentaire de Chimie
Lavoisier's Traité Élémentaire de Chimie
By Lavoisier, Antoine-Laurent de - https://libserv.aip.org/ipac20/ipac.jsp?session=1C68700M5Q428.396962&profile=rev-all&source=~!horizon&view=subscriptionsummary&uri=full=3100006~!44241~!3&ri=17&aspect=power&menu=search&ipp=20&spp=20&staffonly=&term=Trait%C3%A9+%C3%A9l%C3%A9mentaire+de+Chimie&index=.GW&uindex=&aspect=power&menu=search&ri=17, Public domain, https://commons.wikimedia.org/w/index.php?curid=125621155
1800 CE

Volta Invents the Electric Battery

Alessandro Volta creates the voltaic pile, enabling electrolysis and the discovery of new elements. #chemistry #physics

Volta Invents the Electric Battery
Volta Invents the Electric Battery
By Borbrav, svg version by Luigi Chiesa - Image:Voltaic pile.png, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=5091724
1803 CE

Dalton's Atomic Theory

John Dalton proposes atomic theory with atomic weights, explaining chemical reactions as combinations of atoms. #chemistry #science

Dalton's Atomic Theory
Dalton's Atomic Theory
By Thomas Phillips - National Portrait Gallery, London, Public domain, https://commons.wikimedia.org/w/index.php?curid=11727058
1807 CE

Davy Discovers Sodium and Potassium

Humphry Davy uses electrolysis to isolate sodium, potassium, and other alkali metals, expanding the element list. #chemistry #discovery

Davy Discovers Sodium and Potassium
Davy Discovers Sodium and Potassium
By Thomas Phillips - one or more third parties have made copyright claims against Wikimedia Commons in relation to the work from which this is sourced or a purely mechanical reproduction thereof. This may be due to recognition of the "sweat of the brow" doctrine, allowing works to be eligible for protection through skill and labour, and not purely by originality as is the case in the United States (where this website is hosted). These claims may or may not be valid in all jurisdictions. As such, use of this image in the jurisdiction of the claimant or other countries may be regarded as copyright infringement. Please see Commons:When to use the PD-Art tag for more information., Public domain, https://commons.wikimedia.org/w/index.php?curid=6364758
1811 CE

Avogadro's Molecular Hypothesis

Amedeo Avogadro proposes that equal volumes of gases contain equal numbers of molecules, distinguishing atoms from molecules. #chemistry #physics

1828 CE

Wöhler Synthesizes Urea

Friedrich Wöhler synthesizes urea from inorganic compounds, disproving vitalism and founding organic chemistry. #chemistry #organic

Wöhler Synthesizes Urea
Wöhler Synthesizes Urea
By Rudolph Hoffmann - Eigenes Foto einer Originallithographie der ÖNB (Wien), Public domain, https://commons.wikimedia.org/w/index.php?curid=16652576
1834 CE

Faraday's Laws of Electrolysis

Michael Faraday formulates laws of electrolysis, quantifying the relationship between electricity and chemical change. #chemistry #physics

Faraday's Laws of Electrolysis
Faraday's Laws of Electrolysis
By Thomas Phillips - Thomas Phillips, 1842, Public domain, https://commons.wikimedia.org/w/index.php?curid=463384
1858 CE

Kekulé Proposes Carbon Tetravalence

August Kekulé establishes that carbon is tetravalent and can form chains, laying the basis for structural organic chemistry. #chemistry #organic

Kekulé Proposes Carbon Tetravalence
Kekulé Proposes Carbon Tetravalence
By Unknown author - https://www.gettyimages.ie/detail/news-photo/german-organic-chemist-friedrich-august-kekule-von-news-photo/72242781, Public domain, https://commons.wikimedia.org/w/index.php?curid=167877
1865 CE

Kekulé's Benzene Structure

Kekulé proposes the cyclic structure of benzene, revolutionizing aromatic chemistry. #chemistry #organic

Kekulé's Benzene Structure
Kekulé's Benzene Structure
By Laurent Mazouin at lb.wikipedia - Own work Transferred from lb.wikipedia, Public domain, https://commons.wikimedia.org/w/index.php?curid=1379125
1869 CE

Mendeleev's Periodic Table

Dmitri Mendeleev publishes the first periodic table, arranging elements by atomic weight and predicting undiscovered elements. #chemistry #periodictable

Mendeleev's Periodic Table
Mendeleev's Periodic Table
By Lekritz - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=185001042
1874 CE

van't Hoff's Tetrahedral Carbon

Jacobus van't Hoff proposes the tetrahedral geometry of carbon, explaining optical isomerism and stereochemistry. #chemistry #stereochemistry

van't Hoff's Tetrahedral Carbon
van't Hoff's Tetrahedral Carbon
By Nicola Perscheid - one or more third parties have made copyright claims against Wikimedia Commons in relation to the work from which this is sourced or a purely mechanical reproduction thereof. This may be due to recognition of the "sweat of the brow" doctrine, allowing works to be eligible for protection through skill and labour, and not purely by originality as is the case in the United States (where this website is hosted). These claims may or may not be valid in all jurisdictions. As such, use of this image in the jurisdiction of the claimant or other countries may be regarded as copyright infringement. Please see Commons:When to use the PD-Art tag for more information., Public domain, https://commons.wikimedia.org/w/index.php?curid=44101635
1884 CE

Arrhenius Proposes Ionic Dissociation

Svante Arrhenius presents the theory of electrolytic dissociation, explaining conductivity of solutions. #chemistry #physical

Arrhenius Proposes Ionic Dissociation
Arrhenius Proposes Ionic Dissociation
By Photogravure Meisenbach Riffarth & Co. Leipzig. - Zeitschrift für Physikalische Chemie, Band 69, 1909., Public domain, https://commons.wikimedia.org/w/index.php?curid=96273
1895 CE

Röntgen Discovers X-Rays

Wilhelm Röntgen discovers X-rays, leading to new analytical techniques in chemistry and medicine. #chemistry #physics

Röntgen Discovers X-Rays
Röntgen Discovers X-Rays
By Erwin Hanfstaengl - https://global.museum-digital.org/singleimage?imagenr=2399678, Public domain, https://commons.wikimedia.org/w/index.php?curid=182243188
1896 CE

Becquerel Discovers Radioactivity

Henri Becquerel discovers radioactivity in uranium salts, opening the field of nuclear chemistry. #chemistry #physics

Becquerel Discovers Radioactivity
Becquerel Discovers Radioactivity
By Paul Nadar / Adam Cuerden - This file comes from Gallica Digital Library and is available under the digital ID btv1b532297273/f1, Public domain, https://commons.wikimedia.org/w/index.php?curid=120421283
1897 CE

Thomson Discovers the Electron

J.J. Thomson identifies the electron, the first subatomic particle, revolutionizing atomic theory. #chemistry #physics

Thomson Discovers the Electron
Thomson Discovers the Electron
By Not Mentioned - First World War.com, Public domain, https://commons.wikimedia.org/w/index.php?curid=2969861
1900 CE

Planck's Quantum Hypothesis

Max Planck introduces quantum theory to explain blackbody radiation, laying the foundation for quantum chemistry. #chemistry #physics

Planck's Quantum Hypothesis
Planck's Quantum Hypothesis
By Hugo Erfurth - This file was derived from: Max Planck by Hugo Erfurth 1938cr.jpg Original source: https://www.dhm.de/lemo/bestand/objekt/max-planck, Public domain, https://commons.wikimedia.org/w/index.php?curid=153625300
1909 CE

Rutherford's Gold Foil Experiment

Ernest Rutherford discovers the atomic nucleus through alpha particle scattering, leading to the nuclear model. #chemistry #physics

1913 CE

Moseley's Atomic Number Law

Henry Moseley establishes atomic number as the basis for periodic table ordering, resolving inconsistencies. #chemistry #physics

Moseley's Atomic Number Law
Moseley's Atomic Number Law
By AIP Emilio Segre Visual Archives, W. F. Meggers Gallery of Nobel Laureates - https://ru.wikipedia.org/wiki/%D0%A4%D0%B0%D0%B9%D0%BB:Moseley_henry.jpg, Public domain, https://commons.wikimedia.org/w/index.php?curid=39775530
1913 CE

Bohr's Atomic Model

Niels Bohr proposes a quantized electron orbit model, explaining hydrogen spectra and advancing quantum chemistry. #chemistry #physics

Bohr's Atomic Model
Bohr's Atomic Model
By JabberWok at English Wikipedia - Transferred from en.wikipedia to Commons., CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=2639910
1916 CE

Lewis's Covalent Bond Theory

Gilbert N. Lewis proposes the electron-pair bond and Lewis dot structures, explaining chemical bonding. #chemistry #bonding

1923 CE

Brønsted–Lowry Acid–Base Theory

Johannes Brønsted and Thomas Lowry independently define acids as proton donors and bases as proton acceptors. #chemistry #acids

1925 CE

Pauli Exclusion Principle

Wolfgang Pauli formulates the exclusion principle, stating no two electrons can have identical quantum numbers. #chemistry #physics

Pauli Exclusion Principle
Pauli Exclusion Principle
By Unknown author, Public domain, https://commons.wikimedia.org/w/index.php?curid=333866
1926 CE

Schrödinger's Wave Equation

Erwin Schrödinger develops the wave equation for quantum mechanics, enabling calculation of electron orbitals. #chemistry #physics

1927 CE

Heisenberg's Uncertainty Principle

Werner Heisenberg states the uncertainty principle, limiting simultaneous knowledge of position and momentum. #chemistry #physics

Heisenberg's Uncertainty Principle
Heisenberg's Uncertainty Principle
By Unknown author - This image was provided to Wikimedia Commons by the German Federal Archive (Deutsches Bundesarchiv) as part of a cooperation project. The German Federal Archive guarantees an authentic representation only using the originals (negative and/or positive), resp. the digitalization of the originals as provided by the Digital Image Archive., CC BY-SA 3.0 de, https://commons.wikimedia.org/w/index.php?curid=5436254
1931 CE

Pauling's Resonance Theory

Linus Pauling introduces resonance theory to describe bonding in molecules like benzene, advancing quantum chemistry. #chemistry #bonding

Pauling's Resonance Theory
Pauling's Resonance Theory
By Unknown author - Oregon State University [1], CC BY-SA 2.0, https://commons.wikimedia.org/w/index.php?curid=144490366
1932 CE

Chadwick Discovers the Neutron

James Chadwick discovers the neutron, enabling the understanding of isotopes and nuclear reactions. #chemistry #physics

Chadwick Discovers the Neutron
Chadwick Discovers the Neutron
By Los Alamos National Laboratory, Attribution, https://commons.wikimedia.org/w/index.php?curid=36283260
1940 CE

Seaborg Synthesizes Plutonium

Glenn Seaborg and team synthesize plutonium, expanding the periodic table with transuranium elements. #chemistry #nuclear

Seaborg Synthesizes Plutonium
Seaborg Synthesizes Plutonium
By Atomic Energy Commission. (1946 - 01/19/1975) - NAIL Control Number: NWDNS-326-COM-12 NARA (enter "Glenn Seaborg" in search form under Digital Copies tab), Public domain, https://commons.wikimedia.org/w/index.php?curid=1390573
1953 CE

Watson and Crick Discover DNA Structure

James Watson and Francis Crick propose the double helix structure of DNA, revolutionizing biochemistry. #chemistry #biology

Watson and Crick Discover DNA Structure
Watson and Crick Discover DNA Structure
By Zephyris - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=15027555
1965 CE

Woodward–Hoffmann Rules

Robert Burns Woodward and Roald Hoffmann develop rules for pericyclic reactions, a milestone in theoretical organic chemistry. #chemistry #organic

Woodward–Hoffmann Rules
Woodward–Hoffmann Rules
By Ivogt - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=23034878
1985 CE

Discovery of Fullerenes

Harry Kroto, Robert Curl, and Richard Smalley discover buckminsterfullerene (C60), a new carbon allotrope. #chemistry #nanotechnology

Discovery of Fullerenes
Discovery of Fullerenes
By 痛 - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=118428240
1991 CE

Discovery of Carbon Nanotubes

Sumio Iijima discovers carbon nanotubes, leading to advances in materials science and nanotechnology. #chemistry #nanotechnology

Discovery of Carbon Nanotubes
Discovery of Carbon Nanotubes
By Original hochgeladen von Schwarzm am 30. Aug 2004; Selbst gemacht mit C4D/Cartoonrenderer, GNU FDL - German Wikipedia, original upload 29. Dez 2004 by APPER, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=350208
2016 CE

Four New Elements Named

IUPAC officially names nihonium, moscovium, tennessine, and oganesson, completing period 7 of the periodic table. #chemistry #periodictable