Alexander Fleming: Discovery of Penicillin & Antibiotic Era
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Biographical timeline of Sir Alexander Fleming, the Scottish bacteriologist who discovered penicillin and laid the foundation for modern antibiotics, from his birth in 1881 to his death in 1955.
Chronological Storyline (34 Milestones)
Aug 6, 1881 CE
Birth of Alexander Fleming
Alexander Fleming is born on a farm near Darvel, in Ayrshire, Scotland. #medicine #biography
Birth of Alexander Fleming By Official photographer - http://media.iwm.org.uk/iwm/mediaLib//32/media-32192/large.jpg This photograph TR 1468 comes from the collections of the Imperial War Museums., Public domain, https://commons.wikimedia.org/w/index.php?curid=24436974
1885 CE
Family Moves to Darvel
Fleming's family moves to Darvel, where he begins attending Loudoun Moor School. #education #biography
1894 CE
Moves to London
At age 13, Fleming moves to London to live with his elder brother, Thomas, and attends the Regent Street Polytechnic. #education #biography
1901 CE
Works in Shipping Office
Fleming works as a clerk in a shipping office, a job he dislikes, but which funds his medical studies. #career #biography
1903 CE
Enters St Mary's Hospital Medical School
Fleming enrols at St Mary's Hospital Medical School in London, after inheriting a small legacy. #education #medicine
1906 CE
Qualifies in Medicine
Fleming graduates with an MBBS degree with distinction from the University of London. #medicine #education
1908 CE
Earns BSc in Bacteriology
Fleming receives a BSc degree in bacteriology from the University of London. #science #education
1909 CE
Gold Medal in Bacteriology
Fleming is awarded the Gold Medal in Bacteriology from the University of London. #achievement #science
1914 CE
WWI Military Service Begins
Fleming is commissioned as a lieutenant in the Royal Army Medical Corps and serves in World War I, studying wound infections. #medicine #war
Dec 23, 1915 CE
Marries Sarah Marion McElroy
Fleming marries Sarah Marion McElroy, a nurse from Ireland, who later dies in 1949. #personal #biography
1918 CE
Demobilization and Return to St Mary's
After WWI, Fleming returns to St Mary's Hospital, where he works with Almroth Wright on bacteriological research. #medicine #career
Dec 1, 1921 CE
Discovery of Lysozyme
Fleming discovers lysozyme, an antibacterial enzyme found in tears and mucus, marking his first major scientific discovery. #science #discovery
Discovery of Lysozyme By Yikrazuul - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=204021
1922 CE
Publishes Lysozyme Research
Fleming publishes his findings on lysozyme in the Proceedings of the Royal Society. #science #publication
Sep 28, 1928 CE
Discovery of Penicillin Mold
Fleming notices that a mold (Penicillium notatum) has inhibited bacterial growth in a Petri dish, leading to the discovery of penicillin. #science #discovery #microbiology
Discovery of Penicillin Mold By Yikrazuul - Own work, Public domain, https://commons.wikimedia.org/w/index.php?curid=7348509
1928 CE
Appointed Professor of Bacteriology
Fleming is appointed Professor of Bacteriology at the University of London, based at St Mary's Hospital. #career #medicine
Jun 1, 1929 CE
Publishes Penicillin Paper
Fleming publishes his paper on penicillin in the British Journal of Experimental Pathology, but struggles to isolate the compound. #science #publication
1930 CE
Continues Penicillin Research
Fleming continues to experiment with penicillin, using it as a topical antiseptic, but fails to produce it in large quantities. #science #medicine
1940 CE
Florey and Chain Begin Mass Production
Howard Florey, Ernst Chain, and their team at Oxford University begin large-scale production and purification of penicillin. #science #medicine
Feb 12, 1941 CE
First Human Treated with Penicillin
The first human patient, Albert Alexander, receives penicillin and initially improves, but dies due to insufficient supply. #medicine #history
1942 CE
Penicillin Production in the US
US pharmaceutical companies begin mass-producing penicillin, aided by government support, making the drug widely available. #science #medicine
1943 CE
Elected Fellow of the Royal Society
Fleming is elected a Fellow of the Royal Society (FRS) for his contributions to bacteriology. #honor #science
1944 CE
Knighted by King George VI
Fleming is knighted for his role in the discovery of penicillin, becoming Sir Alexander Fleming. #honor #biography
Oct 1, 1945 CE
Awarded Nobel Prize in Physiology or Medicine
Fleming shares the Nobel Prize with Howard Florey and Ernst Chain for the discovery of penicillin and its curative effects. #award #medicine
1946 CE
Receives Albert Medal
Fleming is awarded the Albert Medal by the Royal Society of Arts for his contributions to the arts, manufactures, and commerce. #honor #achievement
1947 CE
Awarded French Legion of Honour
Fleming receives the French Legion of Honour for his scientific achievements. #honor #international
1948 CE
Awarded Order of the Phoenix (Greece)
The Greek government awards Fleming the Order of the Phoenix for his contributions to medicine. #honor #international
Sep 1, 1949 CE
First Wife Dies
Sarah Marion Fleming passes away, leaving Fleming widowed after 34 years of marriage. #personal #biography
1951 CE
Honorary Citizenship of Paris
Fleming receives honorary citizenship of Paris for his contributions to medicine. #honor #international
1951 CE
Appointed Lord Rector of Edinburgh University
Fleming is elected Lord Rector of the University of Edinburgh, serving until 1954. #education #honor
Apr 11, 1953 CE
Marries Amalia Koutsouri-Vourekas
Fleming marries Amalia Koutsouri-Vourekas, a Greek bacteriologist, in London. #personal #biography
1954 CE
Retirement from Active Research
Fleming steps back from active laboratory research, though he continues to give lectures and receive honors. #career #biography
Mar 11, 1955 CE
Death of Alexander Fleming
Sir Alexander Fleming dies of a heart attack at his home in London, aged 73. #obituary #biography
Mar 18, 1955 CE
Burial at St. Paul's Cathedral
Fleming is buried in St. Paul's Cathedral, London, alongside other British notables. #history #biography
1955 CE
Posthumous Honors and Legacy
Fleming's legacy is celebrated worldwide, with numerous statues, schools, and hospitals named after him. #legacy #medicine