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Alexander Fleming: Discovery of Penicillin & Antibiotic Era

Encyclopedia/1. The Cosmos & The Natural World/6. Medicine & Human Biology/07. Medical & Health Biographies  •  Curated by Admin Timeline.sg

Biographical timeline of Sir Alexander Fleming, the Scottish bacteriologist who discovered penicillin and laid the foundation for modern antibiotics, from his birth in 1881 to his death in 1955.

Chronological Storyline (34 Milestones)

Aug 6, 1881 CE

Birth of Alexander Fleming

Alexander Fleming is born on a farm near Darvel, in Ayrshire, Scotland. #medicine #biography

Birth of Alexander Fleming
Birth of Alexander Fleming
By Official photographer - http://media.iwm.org.uk/iwm/mediaLib//32/media-32192/large.jpg This photograph TR 1468 comes from the collections of the Imperial War Museums., Public domain, https://commons.wikimedia.org/w/index.php?curid=24436974
1885 CE

Family Moves to Darvel

Fleming's family moves to Darvel, where he begins attending Loudoun Moor School. #education #biography

1894 CE

Moves to London

At age 13, Fleming moves to London to live with his elder brother, Thomas, and attends the Regent Street Polytechnic. #education #biography

1901 CE

Works in Shipping Office

Fleming works as a clerk in a shipping office, a job he dislikes, but which funds his medical studies. #career #biography

1903 CE

Enters St Mary's Hospital Medical School

Fleming enrols at St Mary's Hospital Medical School in London, after inheriting a small legacy. #education #medicine

1906 CE

Qualifies in Medicine

Fleming graduates with an MBBS degree with distinction from the University of London. #medicine #education

1908 CE

Earns BSc in Bacteriology

Fleming receives a BSc degree in bacteriology from the University of London. #science #education

1909 CE

Gold Medal in Bacteriology

Fleming is awarded the Gold Medal in Bacteriology from the University of London. #achievement #science

1914 CE

WWI Military Service Begins

Fleming is commissioned as a lieutenant in the Royal Army Medical Corps and serves in World War I, studying wound infections. #medicine #war

Dec 23, 1915 CE

Marries Sarah Marion McElroy

Fleming marries Sarah Marion McElroy, a nurse from Ireland, who later dies in 1949. #personal #biography

1918 CE

Demobilization and Return to St Mary's

After WWI, Fleming returns to St Mary's Hospital, where he works with Almroth Wright on bacteriological research. #medicine #career

Dec 1, 1921 CE

Discovery of Lysozyme

Fleming discovers lysozyme, an antibacterial enzyme found in tears and mucus, marking his first major scientific discovery. #science #discovery

Discovery of Lysozyme
Discovery of Lysozyme
By Yikrazuul - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=204021
1922 CE

Publishes Lysozyme Research

Fleming publishes his findings on lysozyme in the Proceedings of the Royal Society. #science #publication

Sep 28, 1928 CE

Discovery of Penicillin Mold

Fleming notices that a mold (Penicillium notatum) has inhibited bacterial growth in a Petri dish, leading to the discovery of penicillin. #science #discovery #microbiology

Discovery of Penicillin Mold
Discovery of Penicillin Mold
By Yikrazuul - Own work, Public domain, https://commons.wikimedia.org/w/index.php?curid=7348509
1928 CE

Appointed Professor of Bacteriology

Fleming is appointed Professor of Bacteriology at the University of London, based at St Mary's Hospital. #career #medicine

Jun 1, 1929 CE

Publishes Penicillin Paper

Fleming publishes his paper on penicillin in the British Journal of Experimental Pathology, but struggles to isolate the compound. #science #publication

1930 CE

Continues Penicillin Research

Fleming continues to experiment with penicillin, using it as a topical antiseptic, but fails to produce it in large quantities. #science #medicine

1940 CE

Florey and Chain Begin Mass Production

Howard Florey, Ernst Chain, and their team at Oxford University begin large-scale production and purification of penicillin. #science #medicine

Feb 12, 1941 CE

First Human Treated with Penicillin

The first human patient, Albert Alexander, receives penicillin and initially improves, but dies due to insufficient supply. #medicine #history

1942 CE

Penicillin Production in the US

US pharmaceutical companies begin mass-producing penicillin, aided by government support, making the drug widely available. #science #medicine

1943 CE

Elected Fellow of the Royal Society

Fleming is elected a Fellow of the Royal Society (FRS) for his contributions to bacteriology. #honor #science

1944 CE

Knighted by King George VI

Fleming is knighted for his role in the discovery of penicillin, becoming Sir Alexander Fleming. #honor #biography

Oct 1, 1945 CE

Awarded Nobel Prize in Physiology or Medicine

Fleming shares the Nobel Prize with Howard Florey and Ernst Chain for the discovery of penicillin and its curative effects. #award #medicine

1946 CE

Receives Albert Medal

Fleming is awarded the Albert Medal by the Royal Society of Arts for his contributions to the arts, manufactures, and commerce. #honor #achievement

1947 CE

Awarded French Legion of Honour

Fleming receives the French Legion of Honour for his scientific achievements. #honor #international

1948 CE

Awarded Order of the Phoenix (Greece)

The Greek government awards Fleming the Order of the Phoenix for his contributions to medicine. #honor #international

Sep 1, 1949 CE

First Wife Dies

Sarah Marion Fleming passes away, leaving Fleming widowed after 34 years of marriage. #personal #biography

1951 CE

Honorary Citizenship of Paris

Fleming receives honorary citizenship of Paris for his contributions to medicine. #honor #international

1951 CE

Appointed Lord Rector of Edinburgh University

Fleming is elected Lord Rector of the University of Edinburgh, serving until 1954. #education #honor

Apr 11, 1953 CE

Marries Amalia Koutsouri-Vourekas

Fleming marries Amalia Koutsouri-Vourekas, a Greek bacteriologist, in London. #personal #biography

1954 CE

Retirement from Active Research

Fleming steps back from active laboratory research, though he continues to give lectures and receive honors. #career #biography

Mar 11, 1955 CE

Death of Alexander Fleming

Sir Alexander Fleming dies of a heart attack at his home in London, aged 73. #obituary #biography

Mar 18, 1955 CE

Burial at St. Paul's Cathedral

Fleming is buried in St. Paul's Cathedral, London, alongside other British notables. #history #biography

1955 CE

Posthumous Honors and Legacy

Fleming's legacy is celebrated worldwide, with numerous statues, schools, and hospitals named after him. #legacy #medicine