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1.2.1.1 Chemical Engineering

Encyclopedia/1. The Cosmos & The Natural World/2. Physics & Chemistry/03. Chemistry & Periodic Table of Elements  •  Curated by Admin Timeline.sg

Catalysis · Polymer science · Process engineering

Chronological Storyline (37 Milestones)

3000 BCE

Egyptian mummification and early chemistry

Egyptian embalmers and metalworkers developed empirical chemical techniques including calcination, reduction, and the use of natron and organic resins for preservation and metallurgy. · Wikipedia: https://en.wikipedia.org/wiki/History_of_chemistry

Таблица Менделеева по изданию 1871 года с прочерками у предсказанных, но ещё не открытых элементов.
Таблица Менделеева по изданию 1871 года с прочерками у предсказанных, но ещё не открытых элементов.
By The original uploader was Den fjättrade ankan at Swedish Wikipedia. - Källa:Dmitrij Ivanovitj Mendelejev (1834 - 1907). Originally from sv.wikipedia; description page is/was here., Public domain, https://commons.wikimedia.org/w/index.php?curid=1574857
1200 BCE

Indian rasaśāstra mercurial chemistry emerges

Indian alchemical tradition rasaśāstra systematically described the processing of mercury, sulfur, and metal ores for medicinal and metallurgical purposes, influencing later chemical practice. Source — Wikipedia:

300 BCE

Wootz steel produced in India

Indian metallurgists in the Tamil region developed crucible steel (wootz), a high-carbon steel with exceptional properties, later traded to the Middle East and inspiring Damascus steel. Source — Wikipedia:

Watered pattern on iranian sword blade.
Watered pattern on iranian sword blade.
By Rahil Alipour Ata Abadi - Transferred from en.wikipedia to Commons., GFDL, https://commons.wikimedia.org/w/index.php?curid=50800188
200 BCE

Zinc smelting at Zawar, India

Indian metallurgists at Zawar in Rajasthan developed retort distillation to extract metallic zinc from zinc oxide, the earliest known production of metallic zinc in the world. Source — Wikipedia:

300 CE

Ge Hong documents Chinese alchemy

Chinese Taoist alchemist Ge Hong recorded elixir formulas and chemical processes including the purification of cinnabar and the first known description of gunpowder-like reactions in the Baopuzi. Source — Wikipedia:

One of a series of woodcuts of illustrious physicians and legendary founders of Chinese medicine from an edition of Bencao mengquan (Introduction to the Pharmacopoeia), engraved in the Wanli reign period of the Ming dynasty (1573-1620) -- Volume preface, 'Lidai mingyi hua xingshi' (Portraits and names of famous doctors through history). The images are attributed to a Tang (618-907) creator, Gan Bozong. The account in 'Portraits and Names of Famous Doctors through History' states: Ge Hong, a native of Danyang, lived under the Eastern Jin dynasty (317-420). His style-name was Zhichuan, and he also called himself Bao Pu Zi (The one who embraces simplicity). He held the office of magistrate of Gaolou (present-day Beiliu in Guangxi province). He was expert at curing illnesses and well-versed in the classics. A Daoist adept, he knew how to make pills of immortality. He lived as a hermit in Luofu Mountain (a Daoist holy place), where he made pills of immortality and became an Immortal, after which he was known as Ge Xianweng (Ge the Immortal Sage). Ge Hong spent many years in retreat, wandering in the mountains, cultivating himself and writing. He is the author of Bao Pu Zi and Zhouhou jiuzu fang (Book of Remedies in Extremis to be Kept up one's Sleeve) in three volumes.Woodcut By: Gan Bozong (Tang period, 618-907)
One of a series of woodcuts of illustrious physicians and legendary founders of Chinese medicine from an edition of Bencao mengquan (Introduction to the Pharmacopoeia), engraved in the Wanli reign period of the Ming dynasty (1573-1620) -- Volume preface, 'Lidai mingyi hua xingshi' (Portraits and names of famous doctors through history). The images are attributed to a Tang (618-907) creator, Gan Bozong. The account in 'Portraits and Names of Famous Doctors through History' states: Ge Hong, a native of Danyang, lived under the Eastern Jin dynasty (317-420). His style-name was Zhichuan, and he also called himself Bao Pu Zi (The one who embraces simplicity). He held the office of magistrate of Gaolou (present-day Beiliu in Guangxi province). He was expert at curing illnesses and well-versed in the classics. A Daoist adept, he knew how to make pills of immortality. He lived as a hermit in Luofu Mountain (a Daoist holy place), where he made pills of immortality and became an Immortal, after which he was known as Ge Xianweng (Ge the Immortal Sage). Ge Hong spent many years in retreat, wandering in the mountains, cultivating himself and writing. He is the author of Bao Pu Zi and Zhouhou jiuzu fang (Book of Remedies in Extremis to be Kept up one's Sleeve) in three volumes.Woodcut By: Gan Bozong (Tang period, 618-907)
By Gan Bozong (Tang period, 618-907) - https://wellcomeimages.org/indexplus/obf_images/5f/87/4e750c334bb041db425934535c34.jpg (hi-res image) Gallery: https://wellcomeimages.org/indexplus/image/L0039323.html Wellcome Collection gallery (2018-03-28): https://wellcomecollection.org/works/f65bzfbc CC-BY-4.0, CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=33926771
800 CE

Jabir ibn Hayyan founds systematic chemistry

Persian-Arab alchemist Jabir ibn Hayyan introduced systematic laboratory techniques including distillation, crystallization, and the preparation of mineral acids, laying foundations for experimental chemistry. Source — Wikipedia:

15th-century artistic impression of Jabir ibn Hayyan (Geber) from Codici Ashburnhamiani 1166, Biblioteca Medicea Laurenziana, Florence fol 12r
15th-century artistic impression of Jabir ibn Hayyan (Geber) from Codici Ashburnhamiani 1166, Biblioteca Medicea Laurenziana, Florence fol 12r
By Unknown author - https://cdn.britannica.com/10/132710-050-CECF006B/illustration-manuscript-Abu-Musa-Jabir-ibn-Hayyan.jpg, Public domain, https://commons.wikimedia.org/w/index.php?curid=166835469
850 CE

Gunpowder formula published in Wujing Zongyao

Chinese alchemists recorded the first written gunpowder formula in the Wujing Zongyao, a military compendium, marking a milestone in chemical process development with global consequences. Source — Wikipedia:

The earliest known written description of the formula for gunpowder, from the Chinese Wujing Zongyao military manuscript that was compiled by 1044 during the Song Dynasty of China. It was written and compiled by the 11th century Song scholars Zeng Gongliang (曾公亮), Ding Du (丁度), and Yang Weide (楊惟德). The entry for this specific page is headed with the title "method for making the fire-chemical" ("huo yao fa"). This picture can also be found on page 119 of Joseph Needham's book Science and Civilization in China: Volume 5, Part 7.
The earliest known written description of the formula for gunpowder, from the Chinese Wujing Zongyao military manuscript that was compiled by 1044 during the Song Dynasty of China. It was written and compiled by the 11th century Song scholars Zeng Gongliang (曾公亮), Ding Du (丁度), and Yang Weide (楊惟德). The entry for this specific page is headed with the title "method for making the fire-chemical" ("huo yao fa"). This picture can also be found on page 119 of Joseph Needham's book Science and Civilization in China: Volume 5, Part 7.
By PericlesofAthens - Own work (My book), Public domain, https://commons.wikimedia.org/w/index.php?curid=2549290
900 CE

Al-Razi classifies chemical substances

Persian physician and alchemist al-Razi classified substances into spirits, metals, stones, salts, and boraxes, and described the preparation of kerosene from petroleum by distillation. Source — Wikipedia:

Al-Razi classifies chemical substances
Al-Razi classifies chemical substances
By Hossein Behzad - http://sadmu.ir/detail/5999, Public domain, https://commons.wikimedia.org/w/index.php?curid=161546923
1100 CE

Chinese porcelain production perfected

Chinese potters in Jingdezhen perfected high-temperature kiln firing and glaze chemistry for porcelain production, representing an early mastery of high-temperature process engineering. Source — Wikipedia:

China; Jar; Ceramics
China; Jar; Ceramics
By Unknown author - This file was donated to Wikimedia Commons as part of a project by the Metropolitan Museum of Art. See the Image and Data Resources Open Access Policy, CC0, https://commons.wikimedia.org/w/index.php?curid=59373214
1597 CE

Libavius publishes first chemistry textbook

German chemist Andreas Libavius published Alchemia, the first systematic chemistry textbook, organizing chemical knowledge and laboratory procedures into a structured discipline. Source — Wikipedia:

Andreas Libavius (1555 – July 25, 1616) was a German doctor and chemist.
Andreas Libavius (1555 – July 25, 1616) was a German doctor and chemist.
By Unknown author - Unknown source, Public domain, https://commons.wikimedia.org/w/index.php?curid=8949023
1791 CE

Leblanc process for soda ash invented

French chemist Nicolas Leblanc developed a process to produce sodium carbonate from salt and sulfuric acid, becoming one of the first large-scale industrial chemical processes. Source — Wikipedia:

1828 CE

Wöhler synthesizes urea from inorganic compounds

German chemist Friedrich Wöhler synthesized urea from ammonium cyanate, demonstrating that organic compounds could be made from inorganic materials and bridging organic and process chemistry. Source — Wikipedia:

1839 CE

Goodyear discovers vulcanization of rubber

American inventor Charles Goodyear discovered that heating natural rubber with sulfur produced a durable, elastic material, founding the science of polymer cross-linking. Source — Wikipedia:

Worker operating an automatic vulcanization mold at Firestone (General) Tires, Akron, Ohio. The mold is closed by pushing a button, which starts several operations. First the airbag is filled with live steam which circulates during the entire process; next an automatic timer sets itself for the proper length of time and temperature; next pressure is exerted to squeeze the tire into the mold pattern.
Worker operating an automatic vulcanization mold at Firestone (General) Tires, Akron, Ohio. The mold is closed by pushing a button, which starts several operations. First the airbag is filled with live steam which circulates during the entire process; next an automatic timer sets itself for the proper length of time and temperature; next pressure is exerted to squeeze the tire into the mold pattern.
By Alfred T. Palmer - This image is available from the United States Library of Congress's Prints and Photographs division under the digital ID fsa.8b01460.This tag does not indicate the copyright status of the attached work. A normal copyright tag is still required. See Commons:Licensing., Public domain, https://commons.wikimedia.org/w/index.php?curid=14997650
Charles Goodyear
Charles Goodyear
1861 CE

Graham distinguishes colloids and crystalloids

Scottish chemist Thomas Graham coined the term 'colloid' and distinguished colloidal from crystalline substances, founding colloid science essential to polymer and process chemistry. Source — Wikipedia: )

Graham distinguishes colloids and crystalloids
Graham distinguishes colloids and crystalloids
By Unknown author, Public domain, https://commons.wikimedia.org/w/index.php?curid=746876
1863 CE

First chemical engineering course at MIT

MIT offered one of the first formal courses in chemical engineering, taught by William H. Nichols, marking the emergence of chemical engineering as a distinct academic discipline. Source — Wikipedia:

A double effect distillation plant.
A double effect distillation plant.
By User:Luigi Chiesa - Own work, CC BY 3.0, https://commons.wikimedia.org/w/index.php?curid=516874
1869 CE

Hyatt invents celluloid, first synthetic plastic

American inventor John Wesley Hyatt created celluloid from nitrocellulose and camphor, producing the first practical synthetic polymer and launching the plastics industry. Source — Wikipedia:

1873 CE

Norwegian acid-catalyzed esterification studied

Norwegian chemists Peter Waage and Cato Guldberg formulated the law of mass action, providing the thermodynamic basis for understanding catalytic reaction equilibria and rates. Source — Wikipedia:

1888 CE

First chemical engineering degree at MIT

MIT awarded the first Bachelor of Science in Chemical Engineering, formalizing the discipline with a curriculum combining chemistry and mechanical engineering for industrial processes. Source — Wikipedia:

A double effect distillation plant.
A double effect distillation plant.
By User:Luigi Chiesa - Own work, CC BY 3.0, https://commons.wikimedia.org/w/index.php?curid=516874
1895 CE

Haber discovers catalytic ammonia decomposition

German chemist Fritz Haber demonstrated the catalytic decomposition of ammonia, an early step toward the catalytic synthesis of ammonia that would revolutionize fertilizer production. Source — Wikipedia:

Omschrijving: Portret van Professor Fritz Haber, een chemicus uit Duitsland (foto: 1918- 1934).
Omschrijving: Portret van Professor Fritz Haber, een chemicus uit Duitsland (foto: 1918- 1934).
By Unknown author - https://beeldbank.spaarnestadphoto.com/search.pp?flush=1&multikeyword=SFA002023057&searchtype=0#ctr-thumbnails, Public domain, https://commons.wikimedia.org/w/index.php?curid=146075789
1907 CE

Bakelite, first fully synthetic polymer invented

Belgian-American chemist Leo Baekeland invented Bakelite, the first fully synthetic polymer, created from phenol and formaldehyde, founding modern polymer science and the plastics industry. Source — Wikipedia:

Chemical formula of structure of Bakelite
Chemical formula of structure of Bakelite
By Original: MarkusZi Vector: Dirk Hünniger - Bakelit Struktur.png, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=20188781
5th February 1909: Bakelite, the world's first synthetic plastic, announced by Leo Baekeland
5th February 1909: Bakelite, the world's first synthetic plastic, announced by Leo Baekeland
1909 CE

Sabatier wins Nobel for catalytic hydrogenation

French chemist Paul Sabatier received the Nobel Prize for his method of hydrogenating organic compounds using finely divided nickel catalysts, a foundational reaction in catalysis and process engineering. Source — Wikipedia: )

Paul Sabatier (chemist)
Paul Sabatier (chemist)
By Nobel Foundation - http://nobelprize.org/nobel_prizes/chemistry/laureates/1912/sabatier-bio.html, Public domain, https://commons.wikimedia.org/w/index.php?curid=6216618
1913 CE

Haber-Bosch process begins industrial operation

BASF began industrial-scale production of ammonia using the Haber-Bosch process with osmium and iron catalysts, one of the most consequential catalytic processes in human history. Source — Wikipedia:

Chemist Fritz Haber
Chemist Fritz Haber
By The Nobel Foundation - http://nobelprize.org/chemistry/laureates/1918/index.html, Public domain, https://commons.wikimedia.org/w/index.php?curid=365964
Fritz Haber: The Giver and the Taker Away
Fritz Haber: The Giver and the Taker Away
1920 CE

Staudinger proposes macromolecular theory

German chemist Hermann Staudinger proposed that polymers are long-chain molecules of covalently bonded repeating units, founding modern polymer science against prevailing colloid theory. Source — Wikipedia:

Hermann Staudinger
Hermann Staudinger
By Nobel Foundation - Les Prix Nobel en 1953, Public domain, https://commons.wikimedia.org/w/index.php?curid=18542861
1923 CE

Fischer-Tropsch catalytic process developed

German chemists Franz Fischer and Hans Tropsch developed a catalytic process to synthesize liquid hydrocarbons from carbon monoxide and hydrogen, enabling coal-to-liquid fuel production. Source — Wikipedia:

Holzvergaser Güssing 2006 eigene Aufnahme
Holzvergaser Güssing 2006 eigene Aufnahme
By Gerfriedc - Own work, CC BY 2.5, https://commons.wikimedia.org/w/index.php?curid=1402990
1933 CE

Polyethylene discovered by ICI chemists

British chemists Eric Fawcett and Reginald Gibson at Imperial Chemical Industries accidentally discovered polyethylene, which became the world's most widely produced plastic. Source — Wikipedia:

Polyethylene balls.
Polyethylene balls.
By Lluis tgn - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=12749082
1935 CE

Wallace Carothers invents nylon at DuPont

American chemist Wallace Carothers at DuPont synthesized nylon, the first synthetic fiber, representing a triumph of polymer engineering with enormous industrial impact. Source — Wikipedia:

Picture of Wallace Carothers
Picture of Wallace Carothers
By Unknown photographer - http://listverse.com/2007/10/07/top-10-scientists-who-committed-suicide/, Public domain, https://commons.wikimedia.org/w/index.php?curid=13295767
Nylon: First Synthetic Fiber - Decades TV Network
Nylon: First Synthetic Fiber - Decades TV Network
1953 CE

Ziegler discovers titanium catalysts for polyethylene

German chemist Karl Ziegler discovered that titanium chloride and organoaluminum compounds catalyze polyethylene production at mild conditions, revolutionizing industrial polymerization. Source — Wikipedia:

1955 CE

Natta extends Ziegler catalysts to polypropylene

Italian chemist Giulio Natta extended Ziegler's catalysts to produce isotactic polypropylene, enabling stereochemically controlled polymer synthesis and sharing the 1963 Nobel Prize with Ziegler. Source — Wikipedia:

Giulio Natta
Giulio Natta
By Unknown (Mondadori Publishers) - http://www.gettyimages.co.uk/detail/news-photo/portrait-of-italian-engineer-giulio-natta-1960s-news-photo/174304752, Public domain, https://commons.wikimedia.org/w/index.php?curid=41259480
1966 CE

Wilkinson's homogeneous catalyst discovered

British chemist Geoffrey Wilkinson discovered the rhodium-based homogeneous catalyst RhCl(PPh3)3 for hydrogenation, advancing homogeneous catalysis and winning the 1973 Nobel Prize. Source — Wikipedia:

Wilkinson's homogeneous catalyst discovered
Wilkinson's homogeneous catalyst discovered
By Benjah-bmm27 - Own work, Public domain, https://commons.wikimedia.org/w/index.php?curid=2164431
1971 CE

Yuan Longping develops hybrid rice varieties

Chinese agronomist Yuan Longping developed the first high-yield hybrid rice varieties, applying chemical breeding techniques that dramatically increased global food production. Source — Wikipedia:

​9月5日,“杂交水稻之父”袁隆平在湖南长沙接受媒体采访时透露,目前自己和团队正在攻关的超级稻来势很好,可能在10月突破亩产1200公斤大关。
​9月5日,“杂交水稻之父”袁隆平在湖南长沙接受媒体采访时透露,目前自己和团队正在攻关的超级稻来势很好,可能在10月突破亩产1200公斤大关。
By China News Service - YouTube: https://www.youtube.com/watch?v=qsY6qWxCtV4 – View/save archived versions on archive.org 0:35, CC BY 3.0, https://commons.wikimedia.org/w/index.php?curid=105654860
1972 CE

Tu Youyou discovers artemisinin from Artemisia annua

Chinese chemist Tu Youyou isolated artemisinin, a breakthrough antimalarial compound, from traditional Chinese medicine sources using cold extraction, later winning the 2015 Nobel Prize. Source — Wikipedia:

Nobel Laureates in medicin 2015
Nobel Laureates in medicin 2015
By Bengt Nyman from Vaxholm, Sweden - 810_4987 Tu Youyou, medicine, CC BY 2.0, https://commons.wikimedia.org/w/index.php?curid=123803054
1976 CE

Ertl characterizes catalytic surface reactions

German physicist Gerhard Ertl established the molecular-level understanding of catalytic reactions on metal surfaces, including the Haber-Bosch process, winning the 2007 Nobel Prize in Chemistry. Source — Wikipedia:

Prof. Dr. Gerhard Ertl
Prof. Dr. Gerhard Ertl
By Wolfram Däumel - http://www.fhi-berlin.mpg.de/elab/pub/2007-10-10_Ertl/index.html, CC BY-SA 2.0 de, https://commons.wikimedia.org/w/index.php?curid=2962804
1980 CE

Metallocene catalysts revolutionize polymerization

Walter Kaminsky and colleagues discovered that metallocene compounds with methylaluminoxane activators enable precise control of polymer stereochemistry, transforming industrial polymer catalysis. Source — Wikipedia:

2000 CE

Heeger, MacDiarmid, Shirakawa win Nobel for conductive polymers

The Nobel Prize in Chemistry was awarded for the discovery and development of conductive polymers, opening the field of polymer electronics and flexible materials engineering. Source — Wikipedia:

chemical structures of some conductive polymers
chemical structures of some conductive polymers
By Smokefoot - Own work, Public domain, https://commons.wikimedia.org/w/index.php?curid=6893639
2016 CE

Micius satellite demonstrates quantum chemistry in space

China launched the Micius quantum science satellite, enabling quantum-encrypted chemical data transmission and quantum communication experiments relevant to chemical process control. Source — Wikipedia:

2020 CE

mRNA vaccine process engineering at industrial scale

Industrial-scale production of mRNA vaccines for COVID-19 required unprecedented chemical process engineering in lipid nanoparticle formulation and nucleotide synthesis at global scale. Source — Wikipedia:

This video illustrates the details of injection of mRNA (and adenovirus based) vaccines, uptake by the translational machinery of the cell, export, and stimulation of the immune system. The video was originally published in a Danish language article at the popular-science magasine videnskab.dk https://videnskab.dk/forskerzonen/krop-sundhed/hvad-er-rna. The illustrations are made by http://www.movingscience.dk.
This video illustrates the details of injection of mRNA (and adenovirus based) vaccines, uptake by the translational machinery of the cell, export, and stimulation of the immune system. The video was originally published in a Danish language article at the popular-science magasine videnskab.dk https://videnskab.dk/forskerzonen/krop-sundhed/hvad-er-rna. The illustrations are made by http://www.movingscience.dk.
By Lasse Folkersen og Ann-Louise Bergström - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=110274951
2023 CE

AI-driven catalyst discovery accelerates process design

Researchers applied machine learning to predict and design new catalysts and optimize chemical processes, dramatically accelerating chemical engineering research and development. Source — Wikipedia: